Journal ArticleDOI
Immunogenicity and safety of a tetanus toxoid, reduced diphtheria toxoid and three-component acellular pertussis vaccine in adults 19-64 years of age.
Reads0
Chats0
TLDR
In adult recipients, Tdap3v was comparable to an approved TdAP vaccine in providing seroprotection against diphtheria and tetanus, and produced immune responses to pertussis antigens consistent with protection against disease.About:
This article is published in Vaccine.The article was published on 2009-01-29. It has received 59 citations till now. The article focuses on the topics: Diphtheria-Tetanus-acellular Pertussis Vaccines & Toxoid.read more
Citations
More filters
Immunization of health-care personnel: recommendations of the advisory committee on immunization practices (acip)
A Shefer,W Atkinson +1 more
TL;DR: This report updates the previously published summary of recommendations for vaccinating health-care personnel (HCP) and summarizes all current ACIP recommendations for vaccination of HCP and does not contain any new recommendations or policies.
Journal ArticleDOI
How sex and age affect immune responses, susceptibility to infections, and response to vaccination
TL;DR: This review deals with the aging immune system and its interplay with sex steroid hormones and suggests interventions, which distinctively consider the changing level of individual hormones, shall provide potent options in maintaining optimal immune functions.
Journal ArticleDOI
Rationale for pertussis booster vaccination throughout life in Europe
Fred Zepp,Ulrich Heininger,Jussi Mertsola,Ewa Bernatowska,Nicole Guiso,John Roord,Alberto E. Tozzi,Pierre Van Damme +7 more
TL;DR: Recommendations for use of pertussis booster vaccinations at different ages are proposed to reduce individual morbidity and transmission from present rates and increase herd protection.
Journal ArticleDOI
Vaccination in the elderly: an immunological perspective
Wilbur H. Chen,Bernard F. Kozlovsky,Rita B. Effros,Beatrix Grubeck-Loebenstein,Robert R. Edelman,Marcelo B. Sztein +5 more
TL;DR: In this paper, the authors review mechanisms of human immunosenescence and the immune response to currently licensed vaccines and conclude that vaccine responses are blunted in the elderly compared with that of healthy young adults.
Vaccination in the elderly: an immunological perspective
Wilbur H. Chen,Bernard F. Kozlovsky,Rita B. Effros,Beatrix Grubeck-Loebenstein,Robert R. Edelman,Marcelo B. Sztein +5 more
TL;DR: It is concluded that vaccine responses are blunted in the elderly compared with that of healthy young adults and much remains to be learned to improve the effectiveness of next generation vaccines.
References
More filters
Journal ArticleDOI
Comparative analysis of two rates
TL;DR: This paper examines comparative analysis of rates with a view to each of the usual comparative parameters-rate difference, rate ratio and odds ratio with particular reference to first principles, and stresses the need for restricted estimation of variance in the chi-square function underlying interval estimation.
Journal Article
Preventing tetanus, diphtheria, and pertussis among adolescents: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines recommendations of the Advisory Committee on Immunization Practices (ACIP).
Karen R. Broder,Margaret M. Cortese,John K. Iskander,Katrina Kretsinger,Barbara A. Slade,Kristin Brown,Christina M Mijalski,Tejpratap S P Tiwari,Emily J Weston,Amanda C. Cohn,Pamela U. Srivastava,John S. Moran,Benjamin Schwartz,Trudy V. Murphy +13 more
TL;DR: Adolescents aged 11-18 years should receive a single dose of Tdap instead of tetanus and diphtheria toxoids vaccine (Td) for booster immunization against tetanus, diphTheria, and pertussis if they have completed the recommended childhood DTP/DTaP vaccination series.
Journal ArticleDOI
Transmission of Bordetella pertussis to young infants
Aaron M. Wendelboe,Elisabeth Njamkepo,Antoine Bourillon,Daniel Floret,Joel Gaudelus,Michael A. Gerber,Emmanuel Grimprel,David P. Greenberg,Scott A. Halperin,Johannes G. Liese,Flor Munoz-Rivas,Flor Munoz-Rivas,Rémy Teyssou,Nicole Guiso,Annelies Van Rie +14 more
TL;DR: Solid evidence is provided that among infants for whom a source case was identified, household members were responsible for 76%–83% of transmission of Bordetella pertussis to this high-risk group.
Journal ArticleDOI
Infant pertussis: who was the source?
Kristine M. Bisgard,F Brian Pascual,Kristen Ehresmann,Claudia Miller,Christy Cianfrini,Charles E Jennings,Catherine A Rebmann,Julie Gabel,Stephanie Schauer,Susan M. Lett +9 more
TL;DR: Analysis of reported pertussis cases in 4 states with Enhanced Pertussis Surveillance found that among case-infants with an identifiable source, family members were the main source of pertussi transmission to infants.
Journal ArticleDOI
Efficacy of an acellular pertussis vaccine among adolescents and adults
Joel I. Ward,James D. Cherry,Swei-Ju Chang,Susan Partridge,Hang Lee,John J. Treanor,David P. Greenberg,Wendy A. Keitel,Stephen J. Barenkamp,David I. Bernstein,Robert R. Edelman,Kathryn M. Edwards +11 more
TL;DR: The acellular pertussis vaccine was protective among adolescents and adults, and its routine use might reduce the overall disease burden and transmission to children.