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Journal ArticleDOI

Implementation of breast tomosynthesis in a routine screening practice: an observational study

TLDR
The introduction of breast tomosynthesis into clinical practice was associated with a significant reduction in recall rates and a simultaneous increase in breast cancer detection rates.
Abstract
OBJECTIVE. Digital mammography combined with tomosynthesis is gaining clinical acceptance, but data are limited that show its impact in the clinical environment. We assessed the changes in performance measures, if any, after the introduction of tomosynthesis systems into our clinical practice. MATERIALS AND METHODS. In this observational study, we used verified practice- and outcome-related databases to compute and compare recall rates, biopsy rates, cancer detection rates, and positive predictive values for six radiologists who interpreted screening mammography studies without (n = 13,856) and with (n = 9499) the use of tomosynthesis. Two-sided analyses (significance declared at p < 0.05) accounting for reader variability, age of participants, and whether the examination in question was a baseline were performed. RESULTS. For the group as a whole, the introduction and routine use of tomosynthesis resulted in significant observed changes in recall rates from 8.7% to 5.5% (p < 0.001), nonsignificant change...

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Journal ArticleDOI

Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement

TL;DR: The USPSTF concludes that the current evidence is insufficient to assess the benefits and harms of digital breast tomosynthesis (DBT) as a primary screening method for breast cancer.
Journal ArticleDOI

Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography

TL;DR: Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate, and further studies are needed to assess the relationship to clinical outcomes.
Journal ArticleDOI

Effectiveness of Breast Cancer Screening: Systematic Review and Meta-analysis to Update the 2009 U.S. Preventive Services Task Force Recommendation

TL;DR: This systematic review updates evidence for the USPSTF on the effectiveness of mammography screening in reducing breast cancer mortality, all-cause mortality, and advanced breast cancer for women at average risk and how effectiveness varies by age, risk factors, screening intervals, and imaging modalities.
Journal ArticleDOI

Harms of Breast Cancer Screening: Systematic Review to Update the 2009 U.S. Preventive Services Task Force Recommendation.

TL;DR: A systematic review updates evidence for the USPSTF on the harms of breast cancer screening, including false-positive mammography results, overdiagnosis, anxiety, pain during procedures, and radiation exposure, and how these adverse effects vary by age, risk factor, screening interval, and screening modality.
References
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Journal ArticleDOI

Breast Cancer Screening: A Summary of the Evidence for the U.S. Preventive Services Task Force

TL;DR: The goal was to critically appraise and synthesize evidence about the overall effectiveness of breast cancer screening, as well as its effectiveness among women younger than 50 years of age, and to evaluate previous meta-analyses of these trials and of screening test characteristics and studies evaluating the harms associated with false-positive test results.
Journal ArticleDOI

Individual and combined effects of age, breast density, and hormone replacement therapy use on the accuracy of screening mammography.

TL;DR: The accuracy of screening mammography is best in older women and in women with fatty breasts, and the individual and combined effects of age, breast density, and HRT use on mammographic accuracy are examined.
Journal ArticleDOI

Breast Imaging Reporting and Data System: inter- and intraobserver variability in feature analysis and final assessment.

TL;DR: Inter- and intraobserver variability in mammography interpretation is substantial for both feature analysis and management, and continued development of methods to improve standardization in mammographic interpretation is needed.
Journal ArticleDOI

Efficacy of screening mammography. A meta-analysis.

TL;DR: Screening mammography may be effective in reducing breast cancer mortality in women aged 40 to 49 years after 10 to 12 years of follow-up, but the same benefit could probably be achieved by beginning screening at menopause or 50 years of age.
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