Journal ArticleDOI
Incorporation of fluorescent lipids into living rabbit hippocampal and cerebellar slices.
David S. Lester,James L. Olds,Bernard G. Schreurs,Donna L. McPhie,Clive R. Braham,Daniel L. Alkon +5 more
TLDR
The cellular and functional specificity of these fluorescent lipid probes shows great promise for monitoring biochemical events in complex neuronal systems with significant spatial and temporal resolution.About:
This article is published in NeuroImage.The article was published on 1994-11-01. It has received 8 citations till now. The article focuses on the topics: Granule cell & Hippocampal formation.read more
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Journal ArticleDOI
Molecular imaging of lipids in cells and tissues
TL;DR: It is found that imaging TOF-SIMS is a powerful tool for studies of lipid distributions in cells and tissues, enabling the elucidation of their role in cell function and biology.
Journal ArticleDOI
Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry.
TL;DR: It is concluded that the results obtained by using imaging TOF‐SIMS are consistent with known brain and intestine biochemistry and that the localization of fatty acids is specific in differentiated cells.
Journal ArticleDOI
Time-Resolved Imaging of Protein Kinase C Activation during Sea Urchin Egg Fertilization
J. de Barry,Shigenori Kawahara,Ko-Ichi Takamura,Agnes Janoshazi,Yutaka Kirino,James L. Olds,David S. Lester,Daniel L. Alkon,Tohru Yoshioka +8 more
TL;DR: The kinetics and the site distribution of PKC activation appear in complete agreement with the putative functions previously suggested for PKC during fertilization.
Journal ArticleDOI
Applications of fourier transform infrared imaging microscopy in neurotoxicity.
E. Neil Lewis,Linda H. Kidder,Ira W. Levin,Victor F. Kalasinsky,Joseph P. Hanig,David S. Lester +5 more
TL;DR: Spectral imaging extends the power of spectroscopic analysis by generating spatial information while retaining the analytical capability provided by traditional, nonimaging spectroscopies.
Journal ArticleDOI
Cholesterol and phospholipid efflux from cultured cells.
TL;DR: Experimental protocols that can be used in the determination of cholesterol and phospholipid efflux from cultured cells by HDL apolipoproteins for the formation of new HDL particles, and the testing of novel HDL-raising therapies in vitro are described.