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Inhibitory Activities of Flavanone Derivatives Isolated from Sophora flavescens for Melanogenesis

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This article is published in Bulletin of The Korean Chemical Society.The article was published on 2001-01-01 and is currently open access. It has received 30 citations till now. The article focuses on the topics: Sophora flavescens & Flavanone.

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Journal ArticleDOI

Survey and mechanism of skin depigmenting and lightening agents.

TL;DR: The type and amount of melanin synthesized by the melanocyte, and its distribution pattern in the surrounding keratinocytes, determines the actual color of the skin.
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Tyrosinase inhibitory prenylated flavonoids from Sophora flavescens.

TL;DR: For the purpose of the development of a skin-whitening agent, Sophora flavescens was evaluated for tyrosinase inhibitory activity and its active principles were identified following activity-guided isolation.
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Prenylated flavonoids as tyrosinase inhibitors

TL;DR: From the results, kuwanon C, papyriflavonol A, sanggenon D and sophoflavescenol were found to possess the considerable inhibitory activity and the prenylation with isoprenyl group or the vinylation to flavonoid molecules did not enhance tyrosinase inhibitoryActivity.
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Prediction of Tyrosinase Inhibition Activity Using Atom‐Based Bilinear Indices

TL;DR: The results of QSAR studies of tyrosinase inhibitors using the new MDs and linear discriminant analysis (LDA) demonstrate the ability of the bilinear indices in testing biological properties, as well as proposing a new means of molecular parametrization easily calculated from 2D molecular information.
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A new stilbene with tyrosinase inhibitory activity from Chlorophora excelsa.

TL;DR: A new stilbene, 4-[(2"E)-7"-hydroxy-3",7"-dimethyloct-2"-enyl]-2',3,4',5-tetrahydroxy-trans-stilbenes, and the known compound chlorophorin were isolated from the heartwood of Chlorophora excelsa.
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