Journal ArticleDOI
Interactions between the cardiovascular and pain regulatory systems: an updated review of mechanisms and possible alterations in chronic pain.
Stephen Bruehl,Ok Yung Chung +1 more
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TLDR
Theoretical models are presented regarding how chronic pain-related alterations in the mechanisms above and increased pain facilatory system activity (central sensitization) may contribute to altered BP/pain sensitivity interactions in chronic pain.About:
This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 2004-07-01. It has received 319 citations till now. The article focuses on the topics: Chronic pain & Threshold of pain.read more
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Potential Autonomic Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case-Control Study
Roger B. Fillingim,Richard Ohrbach,Joel D. Greenspan,Charles Knott,Ronald Dubner,Eric Bair,Cristina Baraian,Gary D. Slade,William Maixner +8 more
TL;DR: Psychosocial findings from the baseline case-control study of the OPPERA Study, a large prospective cohort study designed to discover causal determinants of TMD pain, indicate significant differences between TMD cases and TMD-free controls across multiple psychossocial constructs, and future analyses will determine whether these psychosocial factors increase risk for new onset TMD.
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Relationships between features of autonomic cardiovascular control and cognitive performance.
TL;DR: The results concerning the on-task measures suggest that a pattern of cardiovascular adjustment including enhanced sympathetic and reduced vagal cardiovascular influences, as well as baroreflex inhibition may induce an adaptive state associated with improved cognitive-attentional functioning.
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Pain perception in athletes compared to normally active controls: a systematic review with meta-analysis.
TL;DR: The data suggest that regular physical activity is associated with specific alterations in pain perception, and psychological and biological factors that may be responsible for these alterations are discussed.
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Sleep disorders and their association with laboratory pain sensitivity in temporomandibular joint disorder.
Michael T. Smith,Emerson M. Wickwire,Edward G. Grace,Robert R. Edwards,Luis F. Buenaver,Stephen Peterson,Brendan Klick,Jennifer A. Haythornthwaite +7 more
TL;DR: High rates of PI and sleep apnea highlight the need to refer TMD patients complaining of sleep disturbance for polysomnographic evaluation and suggest that PI may be linked with central sensitivity and could play an etiologic role in idiopathic pain disorders.
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Heart rate variability and pain: associations of two interrelated homeostatic processes
TL;DR: Inverse associations between measures of resting heart rate variability (HRV), an index of autonomic regulation of heart rate that has been linked to emotionality, and sensitivity to subsequently administered thermal pain suggest pain sensitivity is influenced by characteristics of a central homeostatic system also involved in emotion.
References
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Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry.
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Descending control of pain.
TL;DR: The present review focuses on the organisation of descending pathways and their pathophysiological significance, the role of individual transmitters and specific receptor types in the modulation and expression of mechanisms of descending inhibition and facilitation and the advantages and limitations of established and innovative analgesic strategies which act by manipulation of descending controls.
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Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action.
TL;DR: It is concluded that tricyclic antidepressants in optimal doses appear to be the most efficient treatment of neuropathic pain, but some of the other treatments may be important due to their better tolerability.
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alpha(2)-adrenergic agonists for regional anesthesia - A clinical review of clonidine (1984-1995)
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A systematic review of antidepressants in neuropathic pain
TL;DR: Antidepressants are effective in relieving neuropathic pain and it is still unclear which drug class should be first choice, with very similar results for anticonvulsants.