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Book ChapterDOI

Investigations of the Lung Carcinogenic Potentials of Sodium Dichromate and Cr VI/III Oxide Aerosols in Wistar Rats

Ulrich Glaser, +2 more
- pp 111-116
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TLDR
Cr is not yet a hazard for the general public, but various epidemiological reviews were in the last decades definetively indicative of excessive lung cancer rates among workers exposed in the chromate-producing industry.
Abstract
Cr is not yet a hazard for the general public, but various epidemiological reviews were in the last decades definetively indicative of excessive lung cancer rates among workers exposed in the chromate-producing industry. The carcinogenic risk at several other working places with Cr VI is also suspected (Ref. 1–3).

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Citations
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Journal ArticleDOI

The toxicology of chromium with respect to its chemical speciation: A review

TL;DR: The properties of trivalent and hexavalent chromium are reviewed with respect to acute and chronic oral toxicity, dermal toxicity, systemic toxicity, toxicokinetics, cytotoxicity, genotoxicity and carcinogenicity.
Journal ArticleDOI

Toxicity and Carcinogenicity of Cr(VI) in Animal Models and Humans

TL;DR: There is suggestive evidence that hexavalent Cr causes increased risk of bone, prostate, lymphomas, Hodgkins, leukemia, stomach, genital, renal, and bladder cancer, reflecting the ability of Hexavalent chromate to penetrate all tissues in the body.
Journal ArticleDOI

Semen quality of industrial workers occupationally exposed to chromium.

TL;DR: Exposure to chromium has some effect on human sperm as a significant positive correlation was observed between percentages of abnormal sperm morphology and blood chromium levels, and no significant alterations in semen volume, liquefaction time, mean pH value, sperm viability, concentration or motility were noticed.
Journal Article

Effects of dengue virus infection on peripheral blood cells of mice exposed to hexavalent chromium with drinking water.

TL;DR: The most significant finding of these experiments was that the reduction in platelet counts following inoculation with DV was markedly less in Cr (VI)-fed mice than that in DV-inoculated normal control mice.
Journal ArticleDOI

Thirteen-week subchronic rat inhalation toxicity study with a recovery phase of trivalent chromium compounds, chromic oxide, and basic chromium sulfate.

TL;DR: Significant differences in toxicity to the respiratory tract between trivalent chromium compounds chromic oxide and basic chromium sulfate are likely related to differences in acidity and water solubility, rather than chromium concentration per se.
References
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Journal ArticleDOI

A review of the carcinogenicities of nickel, chromium and arsenic compounds in man and animals.

TL;DR: Human subjects who have developed clinical manifestations of arsenicalism as a result of environmental, occupational or iatrogenic exposures have been reported to have increased incidences of cancers of the skin and possibly of internal organs.
BookDOI

Chromium : Metabolism and Toxicity

TL;DR: The most important and most costly industrial disease is contact dermatitis and the most common cause of that is chromate sensitivity as mentioned in this paper and this collection of monographs, edited by Dr Desmond Burrows is timely and fills an important gap in our literature.
Journal ArticleDOI

Experimental Cancers in Rats Produced by Chromium Compounds and Their Significance to Industry and Public Health

TL;DR: In this article, Experimental Cancers in Rats Produced by Chromium Compounds and Their Significance to Industry and Public Health are discussed. But the authors do not discuss the effects of chromium compounds on human health.
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