Journal ArticleDOI
Iridium(III)-Catalyzed Tandem Annulation Synthesis of Pyrazolo[1,2-α]cinnolines from Pyrazolones and Sulfoxonium Ylides.
Chen-Fei Liu,Man Liu,Lin Dong +2 more
TLDR
A highly efficient iridium-catalyzed cascade annulation of pyrazolones and sulfoxonium ylides to access various pyrazolo[1,2-α]cinnoline derivatives has been achieved and this novel approach expanded the application scope of coupling partners to y lides.Abstract:
A highly efficient iridium-catalyzed cascade annulation of pyrazolones and sulfoxonium ylides to access various pyrazolo[1,2-α]cinnoline derivatives has been achieved. This novel approach expanded the application scope of coupling partners to ylides. The control experiments were performed to give insight into the mechanism of this reaction.read more
Citations
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Journal ArticleDOI
Synthesis of indoles and quinazolines via additive-controlled selective C–H activation/annulation of N-arylamidines and sulfoxonium ylides
Ruizhi Lai,Xiaohua Wu,Songyang Lv,Chen Zhang,Maoyao He,Yuncan Chen,Qiantao Wang,Li Hai,Yong Wu +8 more
TL;DR: Selective synthesis of indole and quinazoline products was achieved through a precise control of the C-H activation/annulation by changing the additives from NaOAc to CuF2/CsOAc.
Journal ArticleDOI
RuII-Catalyzed/NH2-Assisted Selective Alkenyl C-H [5 + 1] Annulation of Alkenylanilines with Sulfoxonium Ylides to Quinolines.
TL;DR: A novel ruthenium-catalyzed [5 + 1] annulation of 2-alkenylanilines with sulfoxonium ylides was developed for the rapid assembly of highly functionalized quinolines and could be obtained with good yields and excellent functional group tolerance.
Journal ArticleDOI
Rhodium-Catalyzed Reaction of Sulfoxonium Ylides and Anthranils toward Indoloindolones via a (4 + 1) Annulation.
TL;DR: A rhodium-catalyzed annulation between aroyl sulfoxonium ylides and anthranils has been developed to synthesize 10H-indolo[1,2-a]indol-10-one derivatives and the Aldol condensation constructed the second indole ring.
Journal ArticleDOI
Rhodium(III)-Catalyzed Regioselective C3-H Acylmethylation of [2,2'-Bipyridine]-6-carboxamides with Sulfoxonium Ylides
TL;DR: A rhodium(III)-catalyzed C-H acylmethylation of tridentate [2,2'-bipyridine]-6-carboxamides was developed, which has a broad range scope of substrates, and exhibits excellent functional group tolerance.
Journal ArticleDOI
Copper-Catalyzed Annulation or Homocoupling of Sulfoxonium Ylides: Synthesis of 2,3-Diaroylquinolines or α,α,β-Tricarbonyl Sulfoxonium Ylides.
TL;DR: An unprecedented copper-catalyzed reaction of sulfoxonium ylides and anthranils is reported that enables an easy access to 2,3-diaroylquinolines through a [4+1+1] annulation.
References
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Journal ArticleDOI
C–C, C–O and C–N bond formation via rhodium(III)-catalyzed oxidative C–H activation
Guoyong Song,Fen Wang,Xingwei Li +2 more
TL;DR: The facile construction of C-E (E = C, N, S, or O) bonds makes Rh(III) catalysis an attractive step-economic approach to value-added molecules from readily available starting materials.
Journal ArticleDOI
Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis
Tetsuya Satoh,Masahiro Miura +1 more
TL;DR: Aromatic substrates with oxygen- and nitrogen-containing substituents undergo oxidative coupling with alkynes and alkenes under rhodium catalysis through regioselective C-H bond cleavage, creating fused-ring systems through these reactions.
Journal ArticleDOI
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
TL;DR: This Review comprehensively highlights recent advances in intra- and intermolecular C-H amination reactions utilizing late transition metal-based catalysts using mechanistic scaffolds and types of reactions.
Journal ArticleDOI
Beyond directing groups: transition-metal-catalyzed C-H activation of simple arenes.
TL;DR: In this review, recent advances in the emerging field of non-chelate-assisted C-H activation are discussed, highlighting some of the most intriguing and inspiring examples of induction of reactivity and selectivity.
Journal ArticleDOI
C–H functionalization logic in total synthesis
Will R. Gutekunst,Phil S. Baran +1 more
TL;DR: This critical review of C-H functionalization logic will be analyzed through the critical lens of total synthesis, and takes the reader through a series of case studies in which it has already been successfully applied.