Journal ArticleDOI
Iron-catalyzed C-C bond formation by direct functionalization of C-H bonds adjacent to heteroatoms.
Zhiping Li,Rong Yu,Haijun Li +2 more
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Transition-metal-catalyzed C H functionalization for the atomand step-economical synthesis of functional molecules has attracted tremendous efforts in both academia and industry, with high efficiency, low cost, and minimal environmental impact.Abstract:
Transition-metal-catalyzed C H functionalization for the atomand step-economical synthesis of functional molecules has attracted tremendous efforts in both academia and industry. The advantages of this method are the high efficiency, low cost, and minimal environmental impact. Heteroatom-containing molecules are abundant in natural products, pharmaceuticals, and materials. It is highly desirable to synthesize these molecules and their derivatives by direct C H functionalization. Metal carbene insertion into a C H bond adjacent to an oxygen atom presents an efficient synthetic approach to ether derivatives (Scheme 1, Meth-read more
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Palladium(II)-catalyzed C-H activation/C-C cross-coupling reactions: versatility and practicality.
TL;DR: A review of palladium-catalyzed coupling of CH bonds with organometallic reagents through a PdII/Pd0 catalytic cycle can be found in this paper.
Journal ArticleDOI
Direct C-H transformation via iron catalysis.
Journal ArticleDOI
The Cross-Dehydrogenative Coupling of C sp 3H Bonds: A Versatile Strategy for CC Bond Formations
TL;DR: This Review highlights the recent progress in the field of cross-dehydrogenative C sp 3C formations and provides a comprehensive overview on existing procedures and employed methodologies.
Journal ArticleDOI
Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups
TL;DR: In this article, a review of the development of utilizing functionalities as directing groups for the construction of C-C and C-hetero bonds via C-H activation using various transition metal catalysts is presented.
References
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Journal ArticleDOI
Activation of c-h bonds by metal complexes
A. E. Shilov,Georgiy B. Shul'pin +1 more
TL;DR: In this article, it was shown that the same alkylhydridoplatinum(IV) complex is the intermediate in the reaction of ethane with platinum(II) σ-complexes.
Journal ArticleDOI
Iron-Catalyzed Reactions in Organic Synthesis
TL;DR: A new iron(III) halide-promoted aza-Prins cyclization between γ,δ-unsaturated tosylamines and aldehydes provides six-membered azacycles in good to excellent yields.
Journal ArticleDOI
C-H Bond Functionalization in Complex Organic Synthesis
Kamil Godula,Dalibor Sames +1 more
TL;DR: In this paper, the functionalization of C-H bonds in complex organic substrates catalyzed by transition metal catalysts is studied and the key concepts and approaches aimed at achieving selectivity in complex settings are discussed.
Journal ArticleDOI
Ru-, Rh-, and Pd-Catalyzed C-C Bond Formation Involving C-H Activation and Addition on Unsaturated Substrates: Reactions and Mechanistic Aspects
C-H bond functionalization in complex organic synthesis
TL;DR: This work outlines the key concepts and approaches aimed at achieving selectivity in complex settings and discusses the impact these reactions have on synthetic planning and strategy in organic synthesis.
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