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Open AccessJournal ArticleDOI

Is obesity still increasing among pregnant women? Prepregnancy obesity trends in 20 states, 2003-2009.

TLDR
Overall, prepregnancy obesity prevalence continues to increase and varies by race-ethnicity and maternal age and the need to address obesity as a key component of preconception care, particularly among high-risk groups is highlighted.
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This article is published in Preventive Medicine.The article was published on 2013-06-01 and is currently open access. It has received 236 citations till now.

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Prenatal exposure to very severe maternal obesity is associated with adverse neuropsychiatric outcomes in children.

TL;DR: Prenatal maternal very severe obesity remained a significant predictor of child neuropsychiatric problems across multiple scales independent of demographic factors, prenatal factors and maternal concurrent symptoms of anxiety and depression.
Journal ArticleDOI

Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet

TL;DR: Maternal diet plays a central role in determining follicular reserve in adult female offspring, and observations suggest that lipid peroxidation and mitochondrial biogenesis are the key intracellular pathways involved in programming of ovarian reserve.
Journal ArticleDOI

Placental function in maternal obesity.

TL;DR: Understanding of how maternal obesity affects the placenta has expanded, and interventions that specifically target placental function, such as activation of placental adiponectin receptors, may prevent the transmission of metabolic disease from obese women to the next generation.
Journal ArticleDOI

Developmental programming by maternal obesity in 2015: Outcomes, mechanisms, and potential interventions.

TL;DR: This review highlights key factors that may mediate programming by maternal obesity, including leptin, insulin, and ghrelin, and explores potential lifestyle and pharmacological interventions in humans and the current state of evidence from animal models.
Journal ArticleDOI

Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.

TL;DR: In overweight/obese pregnancies, the increased FATP2 expression could contribute to increased fatty acid delivery to the fetus and while there is no direct data, it is speculated that this could lead accelerated fetal growth or increased fat deposition.
References
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Journal ArticleDOI

Prevalence and trends in obesity among US adults, 1999-2008.

TL;DR: The increases in the prevalence of obesity previously observed do not appear to be continuing at the same rate over the past 10 years, particularly for women and possibly for men.
Book

Obesity : preventing and managing the global epidemic : report of a WHO Consulation

TL;DR: The fundamental causes of the obesity epidemic are sedentary lifestyles and high-fat energy-dense diets, both resulting from the profound changes taking place in society and the behavioural patterns of communities as a consequence of increased urbanization and industrialization and the disappearance of traditional lifestyles.
Journal ArticleDOI

Expert Committee Recommendations Regarding the Prevention, Assessment, and Treatment of Child and Adolescent Overweight and Obesity: Summary Report

TL;DR: These recommendations recognize the importance of social and environmental change to reduce the obesity epidemic but also identify ways healthcare providers and health care systems can be part of broader efforts.
Journal ArticleDOI

Prevalence of Obesity and Trends in Body Mass Index Among US Children and Adolescents, 1999-2010

TL;DR: The most recent estimates of obesity prevalence in US children and adolescents for 2009-2010 are presented and trend analyses over a 12-year period indicated a significant increase in obesity prevalence between 1999-2000 and 2009- 2010 in males aged 2 through 19 years but not in females.
Journal ArticleDOI

The Obesity Epidemic in the United States—Gender, Age, Socioeconomic, Racial/Ethnic, and Geographic Characteristics: A Systematic Review and Meta-Regression Analysis

TL;DR: Obesity has increased at an alarming rate in the United States over the past three decades and the associations of obesity with gender, age, ethnicity, and socioeconomic status are complex and dynamic.
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