Isolation and identification of two new compounds from Erigeron breviscapus

TLDR: In this article, the chemical constituents of Erigeron breviscapus (Vant.) Hand were investigated and two compounds were identified as 1 hydroxy 2,3,5 trimethoxy xanthone (Ⅴ), and 1 (2′ γ pyranone) 6 caffeoyl α D pyranologlucose (υ�) showed inhibitory effects on the adhesion of endothelial induced by TNF α, indicating its protection against injury due to ischemic reperfusion.

Abstract: Object To investigate the chemical constituents of Erigeron breviscapus (Vant.) Hand. Mazz. (Compositae) Methods Compounds were isolated from the ethanolic extract with column chromatography and identified on the basis of spectral analysis (IR, EI MS, FAB MS, 1HNMR, 13 CNMR, 2DNMR) and physiochemical properties Results Two compounds were identified as 1 hydroxy 2,3,5 trimethoxy xanthone (Ⅴ), and 1 (2′ γ pyranone) 6 caffeoyl α D pyranoglucose (Ⅵ) Conclusion Both of the two compounds were new Compound Ⅵ showed inhibitory effects on the adhesion of endothelial induced by TNF α, indicating its protective effect against injury due to ischemic reperfusion