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Open AccessJournal ArticleDOI

LC-QTOF-MS analysis of xanthone content in different parts of Garcinia mangostana and its influence on cholinesterase inhibition.

Kooi Yeong Khaw, +2 more
- 01 Jul 2020 - 
- Vol. 35, Iss: 1, pp 1433-1441
TLDR
Nonmetric multidimensional scaling analysis revealed α-mangostin and γ-m Mangostin of pericarp as the key metabolites contributing to cholinesterase inhibition.
Abstract: 
Mangosteen is one of the best tasting tropical fruit widely cultivated in Southeast Asia This study aimed to quantify xanthone content in different parts of Garcinia mangostana by LC-QTOF-MS and d

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Neuroprotective Effect of α-Mangostin in the Ameliorating Propionic Acid-Induced Experimental Model of Autism in Wistar Rats.

Aarti Tiwari, +7 more
- 25 Feb 2021 - 
TL;DR: The authors investigated the neuroprotective effect of Alpha-mangostin (AMG) in the rat model of intracerebroventricular-propionic acid (ICV-PPA) induced autism with a confirmation of its effect on the ERK signaling.
Journal ArticleDOI

Volatile and phenolic profiling of a traditional medicinal plant, Hypericum empetrifolium with in vitro biological activities.

Mehmet Boga, +7 more
- 23 May 2021 - 
TL;DR: In this paper, the phytochemical profiles of the essential oil, and two ethanol extracts prepared from the aerial parts (H. empetrifolium aerial parts extract -HEA), and roots of the plant, were analyzed by GC-MS and LC-MS/MS.
Journal ArticleDOI

Antifungal Activity of Alpha-Mangostin against Colletotrichum gloeosporioides In Vitro and In Vivo

Huo-Chun Ye, +6 more
- 16 Nov 2020 - 
TL;DR: Investigation of alpha-mangostin for its antifungal activities and possible mechanism against Colletotrichum gloeosporioides indicated that the protective effect could be superior to the therapeutic effect for mango leaves for scab development and supports α-MG as a natural antIFungal agent in crop protection.
Journal ArticleDOI

Facile Green Synthesis of Titanium Dioxide Nanoparticles by Upcycling Mangosteen (Garcinia mangostana) Pericarp Extract

Eun-Young Erin Ahn, +3 more
- 31 Mar 2022 - 
TL;DR: In this paper , a green synthesis of titanium dioxide nanoparticles (TiO 2 NPs) was performed by upcycling mangosteen ( Garcinia mangostana ) pericarp extract (methanol and ethyl acetate extracts).
Journal ArticleDOI

Coffee Leaves: An Upcoming Novel Food?

Andrea Montis, +6 more
- 24 Sep 2021 - 
TL;DR: In this paper, the authors highlight the biosynthesis, metabolism, and distribution of the 4 main classes of secondary metabolites present in coffee leaves, their main pharmacological and toxicological aspects, and their main roles in planta.
References
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Journal ArticleDOI

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

Nigel H. Greig, +15 more
- 22 Nov 2005 - 
TL;DR: In rats, cymserine analogs caused long-term inhibition of brain BChE and elevated extracellular ACh levels, without inhibitory effects on acetylcholinesterase, and improved the cognitive performance of aged rats.
Journal ArticleDOI

Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders

Melanie-Jayne R. Howes, +2 more
- 01 Jan 2003 - 
TL;DR: Plants and their constituents with pharmacological activities that may be relevant to the treatment of cognitive disorders, including enhancement of cholinergic function in the central nervous system, anti‐cholinesterase (anti‐ChE), antiinflammatory, antioxidant and oestrogenic effects, are discussed.
Journal ArticleDOI

Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa.

Clive Ballard, +3 more
- 16 Jul 2002 - 
TL;DR: The finding that aromatherapy with essential balm oil is a safe and effective treatment for clinically significant agitation in people with severe dementia, with additional benefits for key quality of life parameters, indicates the need for further controlled trials.
Journal ArticleDOI

Natural AChE Inhibitors from Plants and their Contribution to Alzheimer’s Disease Therapy

Ana Paula Murray, +4 more
- 30 Jun 2013 - 
TL;DR: This review summarizes a total of 128 studies which correspond to the most relevant research work published during 2006-2012 (1st semester) on plant-derived compounds, plant extracts and essential oils found to elicit AChE inhibition.
Journal ArticleDOI

Current drug targets for Alzheimer's disease treatment

Debomoy K. Lahiri, +3 more
- 01 Jul 2002 - 
TL;DR: Recent trends in AD research are critically examined from neurochemical to clinical areas to lead to a deeper understanding of the pathobiochemical processes that occur in the AD brain to effectively diagnose and prevent their occurrence.