Journal ArticleDOI
Lipid emulsions in the treatment of acute poisoning: a systematic review of human and animal studies
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TLDR
The quality of evidence was weak and significant heterogeneity prevented data pooling, and available data suggest some benefits of IFE in bupivacaine, verapamil, chlorpromazine, and some tricyclic antidepressants and beta-blockers toxicity.Abstract:
Objective. To assess the evidence regarding the efficacy and safety of intravenous fat emulsion (IFE) in the management of poisoned patients. Methods. We performed a systematic review of the literature with no time or language restriction. The electronic databases were searched from their inception until June 1, 2009 (Medline, EMBASE, ISI web of science, Biological abstract, LILACS, ChemIndex, Toxnet, and Proquest). We also examined the references of identified articles and the gray literature. The target interventions eligible for inclusion were administration of any IFE before, during, or after poisoning in human or animals. All types of studies were reviewed. Eligibility for inclusion and study quality scores, based on criteria by Jadad and the STROBE statement, were evaluated by independent investigators. The primary outcome was mortality. Secondary outcomes included neurologic, hemodynamic, and electrocardiographic variables, as well as adverse effects. Results. Of the 938 publications identified by ...read more
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Part 8: Adult Advanced Cardiovascular Life Support 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
Robert W. Neumar,Charles W. Otto,Mark S. Link,Steven L. Kronick,Michael Shuster,Clifton W. Callaway,Peter J. Kudenchuk,Joseph P. Ornato,Bryan McNally,Scott M. Silvers,Rod S. Passman,Roger D. White,Erik P. Hess,Wanchun Tang,Daniel Davis,Elizabeth Sinz,Laurie J. Morrison +16 more
TL;DR: The goal of therapy for bradycardia or tachycardia is to rapidly identify and treat patients who are hemodynamically unstable or symptomatic due to the arrhythmia.
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Part 12: Cardiac Arrest in Special Situations 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
Terry L. Vanden Hoek,Laurie J. Morrison,Michael Shuster,Michael W. Donnino,Elizabeth Sinz,Eric J. Lavonas,Farida M. Jeejeebhoy,Andrea Gabrielli +7 more
TL;DR: This section of the 2010 AHA Guidelines for CPR and ECC addresses cardiac arrest in situations that require special treatments or procedures beyond those provided during basic life support (BLS) and advanced cardiovascular life support(ACLS).
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Biomimetic enzyme nanocomplexes and their use as antidotes and preventive measures for alcohol intoxication
Yang Liu,Juanjuan Du,Ming Yan,Mo Yin Lau,Jay Hu,Hui Han,Otto O. Yang,Sheng Liang,Wei Wei,Hui Wang,Jianmin Li,Xinyuan Zhu,Linqi Shi,Wei Chen,Cheng Ji,Yunfeng Lu +15 more
TL;DR: It is shown that nanocomplexes containing alcohol oxidase and catalase could reduce blood alcohol levels in intoxicated mice, offering an alternative antidote and prophylactic for alcohol intoxication.
Journal ArticleDOI
Lipid emulsion infusion: resuscitation for local anesthetic and other drug overdose.
TL;DR: This review will focus on the clinical application of lipid emulsion therapy in resuscitation from drug-related toxicity and provide an introduction to the development of the method, guidelines for its use and insights into potential controversies and future applications.
Journal ArticleDOI
Part 10: Special Circumstances of Resuscitation: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
Eric J. Lavonas,Ian R. Drennan,Andrea Gabrielli,Alan C. Heffner,Christopher Hoyte,Aaron Orkin,Kelly N. Sawyer,Michael W. Donnino +7 more
TL;DR: This Part of the 2015 American Heart Association (AHA) Guidelines Update for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC) addresses cardiac arrest in situations that require special treatments or procedures other than those provided during basiclife support (BLS) and advanced cardiovascular life support (ACLS).
References
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Journal ArticleDOI
Assessing the quality of reports of randomized clinical trials : is blinding necessary?
Alejandro R. Jadad,R. A. Moore,Dawn Carroll,C. Jenkinson,David Reynolds,David J. Gavaghan,Henry J McQuay +6 more
TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
Journal Article
The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies
E von Elm,Douglas G. Altman,Matthias Egger,Stuart J. Pocock,Peter C Gøtzsche,Jan P. Vandenbroucke +5 more
Journal ArticleDOI
The hazards of scoring the quality of clinical trials for meta-analysis.
TL;DR: The data indicate that the use of summary scores to identify trials of high quality is problematic, and relevant methodological aspects should be assessed individually and their influence on effect sizes explored.
Book
Clarke's analysis of drugs and poisons
TL;DR: Clarke's analysis of drugs and poisons , Clarke's Analysis of Drugs and poisons, کتابخانه دیجیتال جندی اهواز
Journal ArticleDOI
Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats.
Guy L. Weinberg,Timothy R. VadeBoncouer,Gopal A. Ramaraju,Marcelo F. Garcia-Amaro,Michael J. Cwik +4 more
TL;DR: Lipid infusion shifts the dose‐response to bupivacaine‐induced asystole in rats and suggests a potential application for lipid infusion in treating cardiotoxicity resulting from bupvacaine.
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