Long-term effects of reduced renal mass in humans
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TLDR
In normal individuals, unilateral nephrectomy does not cause progressive renal dysfunction, but may be associated with a small increase in blood pressure.About:
This article is published in Kidney International.The article was published on 1995-09-01 and is currently open access. It has received 225 citations till now. The article focuses on the topics: Nephrectomy & Renal function.read more
Citations
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Morbidity and Mortality After Living Kidney Donation, 1999 2001: Survey of United States Transplant Centers
TL;DR: There have been two recent trends in living kidney donation: increased acceptance of living donors and increasedacceptance of laparoscopic nephrectomy (LN).
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Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy.
Manuel Praga,E. Hernandez,Juan Carlos Herrero,Enrique Morales,Yolanda Revilla,Rafael Diaz-gonzalez,Jose L. Rodicio +6 more
TL;DR: Obese patients are at risk for developing proteinuria and chronic renal failure after unilateral nephrectomy and regular and long-term follow-up is recommended in these patients.
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Meta-Analysis: Risk for Hypertension in Living Kidney Donors
Neil Boudville,G. V. Ramesh Prasad,Greg Knoll,Norman Muirhead,Heather Thiessen-Philbrook,Robert C. Yang,M. Patricia Rosas-Arellano,Abdulrahman Housawi,Amit X. Garg +8 more
TL;DR: This review found 10 studies that compared blood pressure between kidney donors and healthy adults with similar age, sex, and ethnicity and explored whether normotensive adults who donate a kidney develop higher blood pressure and risk for hypertension compared with healthy nondonors acting as control participants.
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Living-Donor Kidney Transplantation: A Review of the Current Practices for the Live Donor
TL;DR: Living donation as practiced for the past 50 yr has been safe with minimal immediate and long-term risk for the donor, but the future experience may not be the same as the authors' society is becoming increasingly obese and developing associated health problems.
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Proteinuria and reduced kidney function in living kidney donors: A systematic review, meta-analysis, and meta-regression
Amit X. Garg,Norman Muirhead,Greg Knoll,Robert C. Yang,G V R Prasad,Heather Thiessen-Philbrook,M. P. Rosas-Arellano,Abdulrahman Housawi,Neil Boudville +8 more
TL;DR: Kidney donation results in small increases in urinary protein and an initial decrement in GFR is not followed by accelerated losses over a subsequent 15 years, and future studies will provide better estimates, and identify those donors at least risk of long-term morbidity.
References
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Prediction of Creatinine Clearance from Serum Creatinine
Donald W. Cockcroft,M H Gault +1 more
TL;DR: A formula has been developed to predict Creatinine clearance from serum creatinine (Scr) in adult males: Ccr = (140 – age) (wt kg)/72 × Scr (mg/100ml) (15% less i).
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Hyperfiltration in remnant nephrons : A potentially adverse response to renal ablation
TL;DR: In this article, a study was performed in three groups of male Munich-Wistar rats 1 wk after surgery: group I, eight control rats that underwent laparotomy and were fed a normal diet.
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Multiple imputation in health-care databases: an overview and some applications.
TL;DR: This paper provides an overview of methods for creating and analysing multiply-imputed data sets, and illustrates the dramatic improvements possible when using multiple rather than single imputation.
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Report of the committee on the genetic constitution of autosomes other than chromosomes 1,2 and 6.
Frank H. Ruddle,P. Meera Khan +1 more
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20 years or more of follow-up of living kidney donors.
TL;DR: It is concluded that perioperative mortality in the USA and Canada after living-donor nephrectomy is low and in long-term follow-up of living donors, there is no evidence of progressive renal deterioration or other serious disorders.