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Journal ArticleDOI

Long-term neurodevelopmental outcome of children born to prospectively followed pregnancies of women with systemic lupus erythematosus and/or antiphospholipid syndrome.

TLDR
Children born to women with SLE and/or APS may need a long-term follow-up focusing on milestones of neurodevelopment in order to detect and correct any alteration as early as possible.
Abstract
BackgroundSystemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome (APS) are autoimmune diseases that affect women of childbearing age. Maternal IgG antiphospholipid antibodies (aP...

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The Role of Brain-Reactive Autoantibodies in Brain Pathology and Cognitive Impairment.

TL;DR: Two different autoimmune conditions and the role of their antibodies in causing brain pathology are described and emerging evidence that pathogenic T cells also play an important role for the disease pathogenesis in NMO since they infiltrate in the CNS.
Journal ArticleDOI

A Review on the Vagus Nerve and Autonomic Nervous System During Fetal Development: Searching for Critical Windows

TL;DR: In this paper, the development of the autonomic nervous system (ANS) during fetal and perinatal life, focusing particularly on the vagus nerve, was reviewed to identify possible "critical windows" that could impact its maturation.
Journal ArticleDOI

Update on Antiphospholipid Syndrome: Ten Topics in 2017.

TL;DR: New findings on long-standing APS, regarding survival, comorbidities, and evolution in other autoimmune conditions, have become available, including new insights into aPL as potential risk factors for damage accrual in SLE and potential implications on neuropsychological involvement of children exposed to maternal aPL in utero.
Journal ArticleDOI

Pediatric antiphospholipid syndrome.

TL;DR: The approach to treatment will be covered, including the unique impact of APS medications on children as compared with adults and the importance of future mechanistic research is emphasized as physicians endeavor to provide the personalized care that children with APS clearly deserve.
Journal ArticleDOI

Pediatric APS: State of the Art.

TL;DR: Recent studies have shown a high prevalence of non-thrombotic manifestations in children with aPL, domains 4/5 specificity of ‘innocent’ anti-β2GPI antibodies in infants, and a higher risk for developmental delays and learning disabilities, hence, the need for neurodevelopmental monitoring in children born to mothers with APS.
References
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Journal ArticleDOI

Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence

TL;DR: The data indicated that the occurrence of psoriasis varied according to age and geographic region, being more frequent in countries more distant from the equator and trends in incidence over time.
Journal ArticleDOI

Prevalence of headache and migraine in children and adolescents: a systematic review of population-based studies.

TL;DR: The aim of this study was to review systematically the prevalence of headache and migraine in children and adolescents and to study the influence of sex, age, and region of residence on the epidemiology.
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Incidence of epilepsy A systematic review and meta-analysis

TL;DR: The results support the need for large population-based incidence studies of epilepsy and provide data that could potentially be used to assess the burden and analyze the trends in incidence of epilepsy.
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Prevalence of atopic dermatitis, asthma, allergic rhinitis, and hand and contact dermatitis in adolescents. The Odense adolescence cohort study on atopic diseases and dermatitis

TL;DR: No population‐based studies have evaluated the prevalence of atopic diseases and hand and contact dermatitis in the same group of adolescents, and epidemiological knowledge is sparse for hand eczema and allergic contact skin disease in this age group.
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