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Open AccessJournal ArticleDOI

Machine learning for medical imaging: methodological failures and recommendations for the future

Gaël Varoquaux, +1 more
- 12 Apr 2022 - 
- Vol. 5, Iss: 1
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TLDR
In this article , the authors review roadblocks to developing and assessing methods in computer analysis of medical images and provide recommendations on how to further address these problems in the future, and also discuss on-going efforts to counteract these problems.
Abstract
Research in computer analysis of medical images bears many promises to improve patients' health. However, a number of systematic challenges are slowing down the progress of the field, from limitations of the data, such as biases, to research incentives, such as optimizing for publication. In this paper we review roadblocks to developing and assessing methods. Building our analysis on evidence from the literature and data challenges, we show that at every step, potential biases can creep in. On a positive note, we also discuss on-going efforts to counteract these problems. Finally we provide recommendations on how to further address these problems in the future.

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References
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Statistical Comparisons of Classifiers over Multiple Data Sets

TL;DR: A set of simple, yet safe and robust non-parametric tests for statistical comparisons of classifiers is recommended: the Wilcoxon signed ranks test for comparison of two classifiers and the Friedman test with the corresponding post-hoc tests for comparisons of more classifiers over multiple data sets.
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TL;DR: This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year, to survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks.
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Do we need hundreds of classifiers to solve real world classification problems

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The paper discusses roadblocks to developing and assessing methods in computer analysis of medical images, including potential biases and limitations of the data.