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In this paper, the Iterative Modeling Process Modeling and Inverse Problems Mechanical Vibrations inverse problems Mathematical and Statistical Aspects of Inverse problems Probability and Statistics Overview Parameter Estimation or Inverse Problem Computation of sigman, Standard Errors, and Confidence Intervals Investigation of Statistical Assumptions Statistically Based Model Comparison Techniques Mass Balance and Mass Transport Introduction Compartmental Concepts Compartment Modeling General Mass Transport Equations Heat Conduction Motivating Problems Mathematical Modeling of Heat Transfer Experimental Modeling: Force/Moments Balance Motivation
Abstract
Introduction: The Iterative Modeling Process Modeling and Inverse Problems Mechanical Vibrations Inverse Problems Mathematical and Statistical Aspects of Inverse Problems Probability and Statistics Overview Parameter Estimation or Inverse Problems Computation of sigman, Standard Errors, and Confidence Intervals Investigation of Statistical Assumptions Statistically Based Model Comparison Techniques Mass Balance and Mass Transport Introduction Compartmental Concepts Compartment Modeling General Mass Transport Equations Heat Conduction Motivating Problems Mathematical Modeling of Heat Transfer Experimental Modeling of Heat Transfer Structural Modeling: Force/Moments Balance Motivation: Control of Acoustics/Structural Interactions Introduction to Mechanics of Elastic Solids Deformations of Beams Separation of Variables: Modes and Mode Shapes Numerical Approximations: Galerkin's Method Energy Functional Formulation The Finite Element Method Experimental Beam Vibration Analysis Beam Vibrational Control and Real-Time Implementation Introduction Controllability and Observability of Linear Systems Design of State Feedback Control Systems and State Estimators Pole Placement (Relocation) Problem Linear Quadratic Regulator Theory Beam Vibrational Control: Real-Time Feedback Control Implementation Wave Propagation Fluid Dynamics Fluid Waves Experimental Modeling of the Wave Equation Size-Structured Population Models Introduction: A Motivating Application A Single Species Model (Malthusian Law) The Logistic Model A Predator/Prey Model A Size-Structured Population Model The Sinko-Streifer Model and Inverse Problems Size Structure and Mosquitofish Populations Appendix A: An Introduction to Fourier Techniques Fourier Series Fourier Transforms Appendix B: Review of Vector Calculus References appear at the end of each chapter.

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Journal ArticleDOI

Physiological modeling of isoprene dynamics in exhaled breath

TL;DR: A thorough modeling study of the end-tidal breath dynamics associated with isoprene, which serves as a paradigmatic example for the class of low-soluble, blood-borne VOCs, is devoted to aid further investigations regarding the exhalation, storage, transport and biotransformation processes associated with this important compound.
Journal ArticleDOI

Parameter Estimation Using Metaheuristics in Systems Biology: A Comprehensive Review

TL;DR: This paper gives a comprehensive review of the application of metaheuristics to optimization problems in systems biology, mainly focusing on the parameter estimation problem (also called the inverse problem or model calibration).
Journal ArticleDOI

A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone

TL;DR: In this article, the authors developed a compartment model that reliably captures these profiles and is capable of relating breath to the systemic concentrations of acetone, with minimal changes of the underlying blood and tissue concentrations.
Journal ArticleDOI

A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone

TL;DR: The chief intention of the present modeling study is to provide mechanistic relationships for further investigating the exhalation kinetics of acetone and other water-soluble species, and is a first step towards new guidelines for breath gas analyses of volatile organic compounds, similar to those for nitric oxide.
Journal ArticleDOI

Estimation of Cell Proliferation Dynamics Using CFSE Data

TL;DR: These investigations suggest that the new decay/label loss and time dependent effective proliferation and death rates do indeed provide improved fits of the model to data, and should prove useful in proliferation assay tracking and modeling, with numerous applications in the biomedical sciences.
References
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Book

Parameter estimation and inverse problems

TL;DR: "Parameter Estimation and Inverse Problems, 2/e" introduces readers to both Classical and Bayesian approaches to linear and nonlinear problems with particular attention paid to computational, mathematical, and statistical issues related to their application to geophysical problems.
Book

Transformation and Weighting in Regression

TL;DR: The Transform-Both-Sides Methodology as mentioned in this paper combines Transformations and Weighting for least square estimation and inference for Variance Functions, which has been applied to generalized least squares and the analysis of heteroscedasticity.
MonographDOI

Vibration of continuous systems

TL;DR: The author explains how basic Equations of Elasticity, Laplace and Fourier Transforms, and Approximate Analytical Methods transformed into Eigenvalue and Modal Analysis Approach, which led to the modern Elastic Wave Propagation.
Book

Nonlinear Models for Repeated Measurement Data

TL;DR: In this paper, nonlinear regression models for individual data are used for analysis of assay data, and Bayesian inference based on linearization is used for linearization of individual estimates, and nonperametric and semiparametric inference.