Journal ArticleDOI
Mathematical derivation of the Jouyban-Acree model to represent solute solubility data in mixed solvents at various temperatures
TLDR
The combined nearly ideal binary solvent/Redlich-Kister model and its extended version, i.e. the Jouyban-Acree model, are the most common models in the solubility prediction area as mentioned in this paper.About:
This article is published in Journal of Molecular Liquids.The article was published on 2018-04-15. It has received 225 citations till now. The article focuses on the topics: Solubility.read more
Citations
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Journal ArticleDOI
Review of the cosolvency models for predicting solubility in solvent mixtures: An update.
TL;DR: There is a gap between available accurate correlative models with the ab initio predictive model and an abinitio accurate prediction is not possible so far and further mathematical efforts are needed to provide such a tool.
Journal ArticleDOI
Thermodynamic analysis and molecular dynamic simulation of the solubility of vortioxetine hydrobromide in three binary solvent mixtures
TL;DR: In this paper, the solubility of Vortioxetine hydrobromide (VORH) was determined by the gravimetric method at temperatures ranging from (283.15 to 318.15) K.
Journal ArticleDOI
Equilibrium solubility, Hansen solubility parameter, dissolution thermodynamics, transfer property and preferential solvation of zonisamide in aqueous binary mixtures of ethanol, acetonitrile, isopropanol and N,N-dimethylformamide
TL;DR: In this article, the authors investigated the equilibrium solubility profile, thermodynamics of dissolution process and solvation performance of zonisamide in aqueous binary mixtures of acetonitrile, ethanol, isopropanol and N,N-dimethylformamide (DMF) by using experiment and mathematical correlations.
Journal ArticleDOI
Solubility Prediction of Drugs in Binary Solvent Mixtures at Various Temperatures Using a Minimum Number of Experimental Data Points.
TL;DR: The model adequately trained using 8 data points could be used as a practical strategy for predicting the solubility of drugs in binary solvent mixtures at various temperatures with acceptable prediction error and using minimum experimental efforts.
Journal ArticleDOI
Solubility of 5-aminosalicylic acid in N-methyl-2-pyrrolidone + water mixtures at various temperatures
Kimia Jouyban,Elnaz Mazaher Haji Agha,Salar Hemmati,Fleming Martínez,Martin Kuentz,Abolghasem Jouyban,Abolghasem Jouyban +6 more
TL;DR: In this article, the authors studied equilibrium solubility of 5-aminosalicylic acid (mesalazine) in mixed solvents using N-methyl-2-pyrrolidone (NMP) and water at T = (293.2 to 313.2) K.
References
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Journal ArticleDOI
Review of the cosolvency models for predicting solubility of drugs in water-cosolvent mixtures
TL;DR: The cosolvency models presented from 1960 to 2007 were reviewed and their accuracies for correlating and/or predicting the solubility of drugs in water-cosolvent mixtures were discussed.
Journal ArticleDOI
Mathematical representation of thermodynamic properties: part ii. derivation of the combined nearly ideal binary solvent(nibs)/redlich-kister mathematical representation from a two-body and three-body interactional mixing model
TL;DR: In this paper, a simple two-body and three-body interactional mixing model is used to derive expressions for the mathematical representation of experimental solute solubilities and activity coefficients in binary solvent mixtures.
Book
Handbook of Solubility Data for Pharmaceuticals
TL;DR: The literature on solubility data for pharmaceuticals has changed in recent years from being mainly concerned with liquid chromatography to gas chromatography and now also includes “solid-phase” data.
Journal ArticleDOI
Thermodynamic properties of nonelectrolyte solution. part 4. estimation and mathematical representation of solute activity coefficients and solubilities in binary solvents using the nibs and modified wilson equations
TL;DR: In this paper, the limitations and applications of the various nearly ideal binary solvent (NIBS) and modified Wilson models for predicting the thermochemical properties of solutes dissolved in binary solvent mixtures are examined using published solute solubility and infinite dilution activity coefficient data for 72 systems.
Journal ArticleDOI
Comparison of models for describing multiple peaks in solubility profiles
TL;DR: In this article, a model derived from the combined nearly ideal binary solvent/Redlich-Kister equation (CNIBS/R-K) for reproducing the experimental solubility curve in mixed solvent systems showing two Solubility maxima is presented.