Molecular epidemiology of adenovirus conjunctivitis in Rio de Janeiro, Brazil, between 2004 and 2007.
Adriana G. Maranhão,Caroline C. Soares,Caroline C. Soares,Maria Carolina M. Albuquerque,Norma Santos +4 more
TLDR
In this paper, the frequency of adenoviral conjunctivitis in the population of Rio de Janeiro, Brazil, between March 2004 and May 2007 and identified the predominant serotype circulating among this population.Abstract:
Viral conjunctivitis is a common, highly contagious disease often caused by adenovirus. We investigate the frequency of adenoviral conjunctivitis in the population of Rio de Janeiro, Brazil, between March 2004 and May 2007 and identified the predominant serotype circulating among this population. Seventy-five ocular swabs were collected from 66 patients with clinical presentation of conjunctivitis. The specimens were analyzed for detection of adenovirus (AdV) by polymerase chain reaction (PCR). The PCR products were further analyzed for virus typing by sequence analysis and/or heteroduplex mobility assay (HMA). Forty-five samples (60%) were positive for AdV of which 21 samples were typed as AdV19 (46.7%), 7 AdV8 (15.5%), 3 AdV31 (6.7%), and one each AdV1, AdV2, AdV3, AdV4 and AdV6. For nine samples the serotype was not determined. AdV19 was the predominant serotype circulating in Rio de Janeiro during the studied period.read more
Citations
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TFOS DEWS II Diagnostic Methodology report
James S. Wolffsohn,Reiko Arita,Robin L. Chalmers,Ali R. Djalilian,Murat Dogru,Kathy Dumbleton,Preeya K. Gupta,Paul M. Karpecki,Sihem Lazreg,Heiko Pult,Benjamin Sullivan,Alan Tomlinson,Louis Tong,Edoardo Villani,Kyung Chul Yoon,Lyndon Jones,Jennifer P. Craig +16 more
TL;DR: The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II Diagnostic Methodology Subcommittee was to identify tests used to diagnose and monitor dry eye disease (DED) to identify those most appropriate to fulfil the definition of DED and its sub-classifications.
Journal ArticleDOI
Human adenovirus: Viral pathogen with increasing importance.
TL;DR: The biology of humanadenovirus (HAdV), the clinical and epidemiological characteristics of adenoviral epidemic keratoconjunctivitis and to present a practical update on its diagnosis, treatment, and prophylaxis are described.
Journal ArticleDOI
Determinants of Outcomes of Adenoviral Keratoconjunctivitis.
Cecilia S Lee,Aaron Y. Lee,Lakshmi Akileswaran,David W. Stroman,Kathryn Najafi-Tagol,Steve Kleiboeker,James Chodosh,Amalia Magaret,Amalia Magaret,Anna Wald,Anna Wald,Russell N. Van Gelder,Gregg J. Berdy,James D. Branch,El-Roy Dixon,Sherif M. El-Harazi,Jack V. Greiner,Joshua Herz,Larry L Lothringer,Damien Macaluso,Andrew L. Moyes,George Nardin,Bernard R. Perez,Lawerence E. Roel,Syamala H.K. Reddy,Stephanie Becker,Neil Shmunes,Stephen J. Smith,Michael Tepedino,Jonathan I. Macy,Prashant Garg,Nivedita Patil,Yasmin Bhagat,Malavika Krishnaswamy,Nagappa Somshekhar,Manisha Acharya,Shree Kumar Reddy,Mary Abraham,Shobha Kini,Nita Shanbag,P.N. Biswas,Virendra Agarwal,Anshu Sahai,P.S. Girija Devi,Vupputuri Venkata Lakshmi,Narasimha Rao,Radhika Tandon,Priti Kapadia,Deepak Mehta,Anju Kochar,Adriana dos Santos Forseto,Rubens Belfort,Jacob Moyses Cohen,Ramon C. Ghanem,Roberta De Ventura,Sergio Luis Gianotti Pimentel,Sérgio Kwitko,Maria Cristina Nishiwaki Dantas,Anna Maria Hofling-Lima,Walton Nosé,D. Wariyapola,M. Wijetunge,Charith Fonseka,Champa Banagala,K.A. Salvin,D.R. Kodikara +65 more
TL;DR: In this article, a randomized, controlled, masked trial for auricloscene for keratoconjunctivitis (NVC-422 phase IIB, NovaBay; clinicaltrials.gov identifier, NCT01877694).
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Adenovirus Ocular Infections: Prevalence, Pathology, Pitfalls, and Practical Pointers.
TL;DR: Although most cases are self-limited and have a relatively benign course, permanent visual disability can occur and it is imperative that all eye care providers are capable of diagnosing and effectively treating these patients, and also preventing the spread of this contagious disease to others.
Journal ArticleDOI
Α molecular epidemiological analysis of adenoviruses from excess conjunctivitis cases
A. Balasopoulou,P. Κokkinos,Dionysios Pagoulatos,Panagiotis Plotas,Olga E Makri,Constantine D. Georgakopoulos,Apostolos Vantarakis +6 more
TL;DR: Molecular analysis could define the cause of viral conjunctivitis, while epidemiological data contributed to the assessment of the risk factors and underlined possible preventive measures.
References
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Rapid Typing of Human Adenoviruses by a General PCR Combined with Restriction Endonuclease Analysis
TL;DR: The PCR-RE digestion method and the nested PCR provide a reliable and sensitive system that can easily be applied to all kinds of clinical samples when rapid identification of adenoviruses is needed.
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A twenty-one year surveillance of adenoviral conjunctivitis in Sapporo, Japan.
Koki Aoki,Yoshitugu Tagawa +1 more
TL;DR: It was found that adenonovirus serotypes 8, 19, and 37 caused severe conjunctivitis without systemic symptoms, whereas serotypes Ad3, Ad7, and Ad11 caused mild conjunctvitis with systemic involvement.
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Adenovirus type 8 epidemic keratoconjunctivitis in an eye clinic : risk factors and control
John A. Jernigan,Barbara S. Lowry,Frederick G. Hayden,Shirley A. Kyger,Brian P. Conway,Dieter H.M. Gröschel,Barry M. Farr +6 more
TL;DR: In conclusion, this outbreak appeared to be due to inadequate disinfection of instruments, especially pneumotonometers, and finger-to-eye transmission by health care workers and hand washing did not reliably remove adenovirus from contaminated fingers.
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Epidemic keratoconjunctivitis and chronic papillary conjunctivitis in London due to adenovirus type 19.
TL;DR: Adenovirus type 19 was identified as a cause of epidemic keratoconjunctivitis in human embryonic kidney cells from 21 patients as mentioned in this paper, the majority were males between 20 and 40 years old.
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An Outbreak of Epidemic Keratoconjunctivitis Caused by a New Intermediate Adenovirus 22/H8 Identified by Molecular Typing
TL;DR: This is, to the authors' knowledge, the first report of a keratoconjunctivitis outbreak caused by an intermediate adenovirus type 22/H8.