scispace - formally typeset
Journal ArticleDOI

Monte Carlo Estimation of Bayesian Credible and HPD Intervals

TLDR
In this article, a Markov chain Monte Carlo (MCMC) sampling algorithm is used to estimate Bayesian credible and highest probability density (HPD) intervals for parameters of interest and provides a simple Monte Carlo approach to approximate these Bayesian intervals when a sample of the relevant parameters can be generated from their respective marginal posterior distribution using a sample from an importance sampling distribution.
Abstract
This article considers how to estimate Bayesian credible and highest probability density (HPD) intervals for parameters of interest and provides a simple Monte Carlo approach to approximate these Bayesian intervals when a sample of the relevant parameters can be generated from their respective marginal posterior distribution using a Markov chain Monte Carlo (MCMC) sampling algorithm. We also develop a Monte Carlo method to compute HPD intervals for the parameters of interest from the desired posterior distribution using a sample from an importance sampling distribution. We apply our methodology to a Bayesian hierarchical model that has a posterior density containing analytically intractable integrals that depend on the (hyper) parameters. We further show that our methods are useful not only for calculating the HPD intervals for the parameters of interest but also for computing the HPD intervals for functions of the parameters. Necessary theory is developed and illustrative examples—including a si...

read more

Citations
More filters
Journal ArticleDOI

Analysis and design of RNA sequencing experiments for identifying isoform regulation

TL;DR: In this paper, a mixture-of-isoforms (MISO) model was proposed to estimate expression of alternatively spliced exons and isoforms and assesses confidence in these estimates.
Book

Doing Bayesian Data Analysis: A Tutorial with R, JAGS, and Stan

TL;DR: Doing Bayesian Data Analysis: A Tutorial with R, JAGS, and Stan provides an accessible approach to Bayesian data analysis, as material is explained clearly with concrete examples.

Analysis and design of RNA sequencing experiments for identifying isoform regulation

TL;DR: The mixture-of-isoforms (MISO) model is developed, a statistical model that estimates expression of alternatively spliced exons and isoforms and assesses confidence in these estimates, providing a probabilistic framework for RNA-seq analysis and functional insights into pre-mRNA processing.
Journal ArticleDOI

Power prior distributions for regression models

TL;DR: In this paper, the authors propose a general class of prior distributions for arbitrary regression models, called power prior distributions, which are based on the idea of raising the likelihood function of the historical data to the power ao, where 0 < ao < 1.
References
More filters
Journal ArticleDOI

Sampling-Based Approaches to Calculating Marginal Densities

TL;DR: In this paper, three sampling-based approaches, namely stochastic substitution, the Gibbs sampler, and the sampling-importance-resampling algorithm, are compared and contrasted in relation to various joint probability structures frequently encountered in applications.
Journal Article

Sampling-based approaches to calculating marginal densities

TL;DR: Stochastic substitution, the Gibbs sampler, and the sampling-importance-resampling algorithm can be viewed as three alternative sampling- (or Monte Carlo-) based approaches to the calculation of numerical estimates of marginal probability distributions.
Book

Statistical Decision Theory and Bayesian Analysis

TL;DR: An overview of statistical decision theory, which emphasizes the use and application of the philosophical ideas and mathematical structure of decision theory.
Book

Approximation Theorems of Mathematical Statistics

TL;DR: In this paper, the basic sample statistics are used for Parametric Inference, and the Asymptotic Theory in Parametric Induction (ATIP) is used to estimate the relative efficiency of given statistics.
Related Papers (5)