Journal ArticleDOI
Myocarditis and cardiomyopathy associated with clozapine
TLDR
Clozapine therapy may be associated with potentially fatal myocarditis and cardiomyopathy in physically healthy young adults with schizophrenia.About:
This article is published in The Lancet.The article was published on 1999-11-27. It has received 478 citations till now. The article focuses on the topics: Cardiomyopathy & Myocarditis.read more
Citations
More filters
Journal ArticleDOI
Physical Health Monitoring of Patients With Schizophrenia
Stephen R. Marder,Susan M. Essock,Alexander L. Miller,Robert W. Buchanan,Daniel E. Casey,John M. Davis,John M. Kane,Jeffrey A. Lieberman,Nina R. Schooler,Nancy H. Covell,Scott Stroup,Ellen M. Weissman,Donna A. Wirshing,Catherine S. Hall,Leonard M. Pogach,Xavier Pi-Sunyer,J. Thomas Bigger,Alan W. Friedman,David L. Kleinberg,Steven J. Yevich,Bonnie M. Davis,Steven S. Shon +21 more
TL;DR: A consensus panel's recommendations for improving the physical health monitoring of patients with schizophrenia who are treated in outpatient settings, including regular monitoring of body mass index, plasma glucose level, lipid profiles, and signs of prolactin elevation or sexual dysfunction are discussed.
Journal ArticleDOI
Update on myocarditis.
Ingrid Kindermann,Christine Barth,Felix Mahfoud,Christian Ukena,Matthias Lenski,Ali Yilmaz,Karin Klingel,Reinhard Kandolf,Udo Sechtem,Leslie T. Cooper,Michael Böhm +10 more
TL;DR: There is some evidence that immunosuppressive and immunomodulating therapy are effective for chronic, virus-negative inflammatory cardiomyopathy, but further investigations by controlled, randomized studies are needed to definitively determine their role in the treatment of myocarditis.
Journal ArticleDOI
Myocarditis: Current Trends in Diagnosis and Treatment
Jared W. Magnani,G. William Dec +1 more
TL;DR: Clinical practice guidelines with regard to its evaluation and treatment are lacking because the wide variety of etiologies implicated in myocarditis and its heterogeneous clinical presentations have impeded patient identification and consensus on the most appropriate diagnostic criteria.
Journal ArticleDOI
Serious mental illness and physical health problems: a discussion paper.
Deborah Robson,Richard Gray +1 more
TL;DR: This discussion paper explores the complex reasons for these disparities in health, such as limitations of health services, the effects of having a serious mental illness, health behaviours and the effect of psychotropic medication.
Journal ArticleDOI
Adverse effects of atypical antipsychotics : differential risk and clinical implications.
Peter M. Haddad,Sonu G Sharma +1 more
TL;DR: It is concluded that broad statements comparing the relative risk of specific adverse effects between ‘atypical’ and ‘conventional’ antipsychotics are largely meaningless; rather, comparisons should be made between specific atypical and specific conventional drugs.
References
More filters
Book
Harrison's Principles of Internal Medicine
TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
Journal ArticleDOI
Excess mortality of schizophrenia. A meta-analysis.
TL;DR: The available evidence suggests that schizophrenia is associated with a large increase mortality from suicide and a moderate increased mortality from natural causes.
Journal ArticleDOI
Clozapine-induced agranulocytosis. Incidence and risk factors in the United States
TL;DR: The increasing risk of agranulocytosis with age and the reduced incidence after the first six months of treatment provide additional guidelines for the prescription and monitoring of clozapine treatment in the future.
Book
Global health statistics: a compendium of incidence prevalence and mortality estimates for over 200 conditions.
TL;DR: This is the second publication in a planned series of 10 volumes that summarize epidemiological knowledge about the major health conditions and risk factors around the world including information on causes of death.
Journal ArticleDOI
Mortality in current and former users of clozapine.
TL;DR: Clozapine (Clozaril®), a tricyclic dibenzodiazepine, causes fewer extrapyramidal side effects than do other antipsychotic drugs, however, it is indicated only for schizophrenia that is not responsive to other therapies.