Journal ArticleDOI
New Preparation of 1,2,4,5-Tetraoxanes
Alexander O. Terent'ev,Alexander V. Kutkin,Zoya A. Starikova,M. Yu. Antipin,Yu. N. Ogibin,Gennady I. Nikishin +5 more
TLDR
In this article, a procedure for the synthesis of 1,2,4,5-tetraoxanes based on the reaction of gem-bishydroperoxycycloalkanes with ketals and acetals catalyzed by boron trifluoride etherate was developed.Abstract:
A convenient procedure was developed for the synthesis of 1,2,4,5-tetraoxanes based on the reaction of gem-bishydroperoxycycloalkanes with ketals and acetals catalyzed by boron trifluoride etherate, which makes it possible to prepare the target products in yields from 13 to 93%.read more
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Journal ArticleDOI
Rearrangements of organic peroxides and related processes
TL;DR: This review is the first to collate and summarize main data on named and unnamed rearrangement reactions of peroxides.
Journal ArticleDOI
Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products
TL;DR: The present review describes the current status of synthetic five and six-membered cyclic peroxides, used in medicine for the design of antimalarial, antihelminthic, and antitumor agents, and the literature from 2000 onwards is surveyed.
Journal ArticleDOI
Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone
Igor V. Alabugin,Leah Kuhn,Michael G. Medvedev,Michael G. Medvedev,Nikolai V. Krivoshchapov,Nikolai V. Krivoshchapov,Vera A. Vil,Ivan A. Yaremenko,Patricia Mehaffy,Meysam Yarie,Alexander O. Terent'ev,Mohammad Ali Zolfigol +11 more
TL;DR: In this article, the authors evaluate the fundamental connections between the anomeric effect and a broad variety of O-functional groups and highlight the vast implications of AE for the structure and reactivity of organic O-functionalities.
Journal ArticleDOI
Tetraoxanes: synthetic and medicinal chemistry perspective.
TL;DR: This study describes the current status of tetraoxane‐based antimalarials that show significant promises because of their artemisinin‐like activity.
Journal ArticleDOI
Synthesis of gem-Dihydroperoxides from Ketones and Aldehydes Using Silica Sulfuric Acid as Heterogeneous Reusable Catalyst
TL;DR: Silica sulfuric acid (SSA) was found to efficiently catalyze the conversion of aldehydes and ketones directly into the corresponding gem-dihydroperoxides (DHPs) on treatment with aqueous 30% H2O2 at room temperature as discussed by the authors.