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New techniques and future perspective of eus for the differential diagnosis of pancreatic malignancies: contrast harmonic imaging

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TLDR
In this article, a contrast-enhanced harmonic EUS system was used to diagnose pancreatic carcinomas as hypovascular masses with a high sensitivity (89-96%) and specificity (64-88%).
Abstract
Although endoscopic ultrasonography (EUS) has the advantage over other imaging methods in that it is possible to obtain high resolution images of the pancreas, it is limited in its ability to characterize pancreatic masses. Contrast-enhanced power Doppler ultrasonography suffers from several limitations such as blooming artifacts, poor spatial resolution, low sensitivity to slow flow and high sensitivity to motion artifacts. Recently, EUS system specific for contrast harmonic imaging has been developed. The use of this EUS system enabled us to observe images of microcirculation and parenchymal perfusion without Doppler-related artifacts in the pancreas. Contrast-enhanced harmonic EUS could diagnose pancreatic carcinomas as hypovascular masses with a high sensitivity (89-96%) and specificity (64-88%). Contrast-enhanced harmonic EUS also discriminates mural nodules from mucous clots in the intraductal papillary mucinous neoplasms.

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Journal ArticleDOI

Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.

TL;DR: The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.
Journal ArticleDOI

Usefulness of contrast-enhanced endoscopic sonography for discriminating mural nodules from mucous clots in intraductal papillary mucinous neoplasms: a single-center prospective study.

TL;DR: The aim of this study was to evaluate the ability of contrast‐enhanced endoscopic sonography for discrimination of mural nodules from mucous clots in intraductal papillary mucinous neoplasms of the pancreas.
Journal ArticleDOI

Differential diagnosis of benign and malignant branch duct intraductal papillary mucinous neoplasm using contrast-enhanced endoscopic ultrasonography

TL;DR: Using CE-EUS to measure MN height provides a highly accurate method for differentiating benign from malignant BD-IPMN.
Journal ArticleDOI

Contrast-enhanced endoscopic ultrasound

TL;DR: CE‐EUS is useful for characterizing pancreatic lesions and can detect pancreatic adenocarcinomas with a sensitivity and specificity of 94% and a specificity of 89% as a result of the hypo‐enhancement of these lesions.
Journal ArticleDOI

Contrast-enhanced endoscopic ultrasonography in digestive diseases

TL;DR: Hemodynamic analysis might be of use for diseases in other organs: upper GI cancer diagnosis, submucosal tumors, and biliary disorders, and it might also provide functional information.
References
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Journal ArticleDOI

Localization of pancreatic endocrine tumors by endoscopic ultrasonography.

TL;DR: Endoscopic ultrasonography is a highly sensitive and specific procedure for the localization of pancreatic endocrine tumors and should be considered for the preoperative localization of such tumors once the clinical and laboratory diagnosis has been established.
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Comparison of endoscopic ultrasonography and multidetector computed tomography for detecting and staging pancreatic cancer.

TL;DR: A prospective study found that, among 80 adults with proven pancreatic cancer, the sensitivity of multidetector computed tomography and endoscopic ultrasonography for detecting a pancreatic mass and detecting resectability was 86% and 98% respectively.
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Endoscopic ultrasound in pancreatic tumor diagnosis

TL;DR: EUS is superior to US and CT and equal to ERCP in pancreatic tumor diagnosis and provides direct visualization of tumor size and shape in almost all patients examined, and should be considered early in the evaluation of patients with suspected pancreatic tumors.
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Endoscopic ultrasonography in the diagnosis and staging of pancreatic adenocarcinoma. Results of a prospective study with comparison to ultrasonography and CT scan.

TL;DR: Endoscopic ultrasonography is an accurate tool for diagnosis and locoregional spread assessment of pancreatic cancer when performed in a reference center, however, EUS does not enable differentiation of pseudotumorous pancreatitis from adenocarcinoma.
Journal ArticleDOI

Dynamic imaging of pancreatic diseases by contrast enhanced coded phase inversion harmonic ultrasonography.

TL;DR: Comparison enhanced coded phase inversion harmonic ultrasonography successfully visualised fine vessels in pancreatic tumours and may play a pivotal role in the depiction and differential diagnosis of pancreatIC tumours.
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