Journal ArticleDOI
New visual acuity charts for clinical research
TLDR
Three new visual acuity charts facilitate quantitative use ofVisual acuity test results by providing high-contrast lettering on washable white polystyrene on which to test right and left eyes.About:
This article is published in American Journal of Ophthalmology.The article was published on 1982-07-01. It has received 2065 citations till now. The article focuses on the topics: Sloan letters & LogMAR chart.read more
Citations
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Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop.
TL;DR: In this article, a process of standardizing the methods for reporting clinical data in the field of uveitis has been discussed, and the results used to develop a series of proposals to better standardize the use of these entities.
Journal ArticleDOI
Ranibizumab and bevacizumab for neovascular age-related macular degeneration.
Daniel F. Martin,Maureen G. Maguire,Gui-Shuang Ying,Juan E. Grunwald,Stuart L. Fine,Glenn J. Jaffe +5 more
TL;DR: Ranibizumab given as needed with monthly evaluation had effects on vision that were equivalent to those of ranibizuab administered monthly, although the comparison between bevacizumAB as needed and monthly bevicizumabs was inconclusive.
Journal ArticleDOI
Development of the 25-item National Eye Institute Visual Function Questionnaire.
TL;DR: Preliminary analyses indicate that the psychometric properties of the NEI VFQ-25 are robust for the eye conditions studied; this suggests that the measure will provide reproducible and valid data when used across multiple conditions of varying severity.
Journal ArticleDOI
Revised indications for the treatment of retinopathy of prematurity results of the early treatment for retinopathy of prematurity randomized trial
TL;DR: Early treatment of high-risk prethreshold ROP significantly reduced unfavorable outcomes to a clinically important degree and led to modified recommendations for the use of peripheral retinal ablation in eyes with ROP.
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Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial
William W. Hauswirth,Tomas S. Aleman,Shalesh Kaushal,Artur V. Cideciyan,Sharon B. Schwartz,Lili Wang,Thomas J. Conlon,Sanford L. Boye,Terence R. Flotte,Barry J. Byrne,Samuel G. Jacobson +10 more
TL;DR: A recombinant adeno-associated virus serotype 2 vector, altered to carry the human RPE65 gene (rAAV2-CBSB-hRPE65) restored vision in animal models with R PE65 deficiency, and Comparisons are drawn between the present work and two other studies of ocular gene therapy for RPE 65-LCA that were carried out contemporaneously and reported.
References
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Journal ArticleDOI
New design principles for visual acuity letter charts.
Ian Bailey,Jan E. Lovie +1 more
TL;DR: In this paper, the authors introduced new principles for the design and use of letter charts for the measurement of visual acuity, and advocated that the test task should be essentially the same at each size level on the chart.
Journal ArticleDOI
Standardized illumination for visual acuity testing in clinical research.
TL;DR: Two boxes are designed, one using direct illumination and the other using retroillumination, to light high-contrast visual acuity charts during testing, and the evenness of the lighting eliminated one of the variables inVisual acuity testing.