Journal ArticleDOI
Nitroprusside infusion does not improve biventricular performance in patients with acute hypoxemic respiratory failure
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TLDR
At a dose resulting in a significant reduction in the mean outflow pressure faced by both the LV and the RV, an infusion of SNP was not associated with any substantial change of forward flow in patients with acute PAH complicating ARF.About:
This article is published in Journal of Critical Care.The article was published on 1986-12-01. It has received 20 citations till now. The article focuses on the topics: Mean blood pressure & Pulmonary hypertension.read more
Citations
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Journal ArticleDOI
The Acute Respiratory Distress Syndrome
TL;DR: New strategies for administering mechanical ventilation to patients with ARDS may reduce the occurrence of iatrogenic volotrauma and oxygen toxicity, accounting in part for the recently observed improvements in patient survival.
Journal ArticleDOI
Response to Inhaled Nitric Oxide in Patients with Acute Right Heart Syndrome
Sangeeta Bhorade,Jeffrey Christenson,Michael O'Connor,Annick Lavoie,Anne S. Pohlman,Jesse B. Hall +5 more
TL;DR: iNO improves hemodynamics in patients with respiratory failure, shock, and right ventricular dysfunction, although mortality was not a key end point in this pilot study, it was high for both responders and nonresponders.
Journal ArticleDOI
Prostacyclin and right ventricular function in patients with pulmonary hypertension associated with ARDS
TL;DR: It is concluded that short term infusions of PGI2 increased CI concomitant to improved RV function parameters when baseline RVEF was depressed and may be useful to lower pulmonary artery pressure in ARDS.
Journal ArticleDOI
Efficacy of Inhaled Nitric Oxide in a Porcine Model of Adult Respiratory Distress Syndrome
Nishit S. Shah,Don K. Nakayama,Timothy D. Jacob,Isuta Nishio,Taiyo Imai,Timothy R. Billiar,Renee Exler,Samuel A. Yousem,Etsuro K. Motoyama,Andrew B. Peitzman +9 more
TL;DR: Inhaled NO appears to be a selective pulmonary vasodilator and may prove to be useful in improving gas exchange in adult respiratory distress syndrome.
Journal ArticleDOI
The pulmonary circulation in acute lung injury: a review of some recent advances.
TL;DR: According to the Starling resistor model of the pulmonary circulation, the pulmonary hypertension of oleic acid lung injury, an experimental model close to the early stage of clinical ARDS, primarly results from an increased vascular closing pressure which exceeds Pla and becomes the effective outflow pressure as mentioned in this paper.
References
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Journal ArticleDOI
Pulmonary Hypertension in Severe Acute Respiratory Failure
TL;DR: The work load imposed upon the right ventricle by elevation of pulmonary vascular resistance may be a factor limiting survival in severe acute respiratory failure.
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The pathophysiology of failure in acute right ventricular hypertension: hemodynamic and biochemical correlations.
TL;DR: It is demonstrated that ischemia is the cause of failure in acute RV hypertension, as evidenced by decreased aortic pressure and cardiac output and increased RV end-diastolic pressure and RV systolic pressure.
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A new technique for assessing right ventricular ejection fraction using rapid multiple-gated equilibrium cardiac blood pool scintigraphy. Description, validation and findings in chronic coronary artery disease.
Jamshid Maddahi,Daniel S. Berman,D.T. Matsuoka,Alan D. Waxman,K.E. Stankus,James S. Forrester,H.J.C. Swan +6 more
TL;DR: In patients with coronary artery disease, RVEF was not significantly different from that in the normal group, regardless of the degree of stenosis of the right coronary artery, and is therefore well suited to serial assessment of right ventricular function during exercise.
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Pharmacological mechanisms for left ventricular unloading in clinical congestive heart failure. Differential effects of nitroprusside, phentolamine, and nitroglycerin on cardiac function and peripheral circulation.
TL;DR: Vasodilators produce disparate modifications of LV function by their differing alterations of preload and impedance, which are dependent upon relative extents of relaxation of systemic resistance and capacitance vessels characteristic of each agent as used clinically.
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Pulmonary hypertension in sepsis: measurement by the pulmonary arterial diastolic-pulmonary wedge pressure gradient and the influence of passive and active factors.
William J. Sibbald,NigelA.M. Paterson,Ronald L. Holliday,Richard A. Anderson,Trevor R. Lobb,John H. Duff +5 more
TL;DR: The presence of pulmonary hypertension in sepis appears to be an active, rather than a passive, phenomenon and unrelated to arterial oxygen saturation or acid-base imbalance.