Nuclear magnetic resonance studies of lecithin bimolecular leaflets with incorporated fluorescent probes.
F Podo,J K Blasie +1 more
TLDR
Pulse Fourier transform proton magnetic resonance techniques have been used to determine the precise location of four membrane fluorescent probe molecules in lipid bilayer model membranes above the gel-to-liquid crystal transition temperature.Abstract:
Pulse Fourier transform proton magnetic resonance techniques have been used to determine (i) the precise location of four membrane fluorescent probe molecules in lipid bilayer model membranes above the gel-to-liquid crystal transition temperature, tm; (ii) the dynamical perturbation of the host lipid molecules induced by incorporation of the probe into the bilayer. The regions of maximal perturbation induced by these probes do not necessarily coincide with their actual location in the bilayer.read more
Citations
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Book ChapterDOI
Effects of Alcohols on Micro-Organisms
TL;DR: The chapter concludes that the basic actions of alcohols on both eukaryotic and prokaryotic organisms share the same general principles.
Journal ArticleDOI
Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysis.
TL;DR: The interaction of free fatty acids with cell membranes and lipid bilayers was studied by monitoring the emission polarization changes of the fluorescent probes 1,6-diphenyl-1,3,5-hexatriene (DPH) and 8-anilino-1-naphthalene sulfonate (ANS), and it was found that cis unsaturated fatty acids incorporated into plasma membranes reduced DPH and increased ANS polarization.
Journal ArticleDOI
1-[4-(Trimethylamino)phenyl]-6-phenylhexa-1,3,5-triene: synthesis, fluorescence properties, and use as a fluorescence probe of lipid bilayers.
TL;DR: TMA-DPH, a cationic analogue of diphenylhexatriene (DPH), has photophysical properties that are generally similar to those of DPH, and should prove useful in the study of the dynamics of phospholipid monolayers, e.g., in native or reconstituted lipoproteins.
Journal ArticleDOI
Effects of ethanol on the Escherichia coli plasma membrane.
K M Dombek,Lonnie O. Ingram +1 more
TL;DR: The results suggest that the regulation of the lipid-to-protein ratio of the plasma membrane may be an important adaptive response of E. coli to growth in the presence of ethanol.
Journal ArticleDOI
Amyloid beta-protein interactions with membranes and cholesterol: causes or casualties of Alzheimer's disease.
TL;DR: It is proposed that modification of the transbilayer distribution of cholesterol in contrast to a change in the total amount of cholesterol provides a cooperative environment for Abeta synthesis and accumulation in membranes leading to cell dysfunction including disruption in cholesterol homeostasis.
References
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Book
Applications of nuclear magnetic resonance spectroscopy in organic chemistry
TL;DR: In this paper, the authors discuss the applications of nuclear magnetic resonance spectroscopy in organic chemistry and propose a fast and easy way to obtain a book for such applications, taking into account that the book can straight get it.