Open AccessDissertation
Nuclear quadrupole double resonance
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TLDR
In this paper, the basic theories of nuclear quadrupole resonance are outlined, together with some basic NMR theory and its application to double resonance technologies, and an improved design of spectrometer using double resonance is presented, including a description of a new flow cryostat which can operate down to 4.2°K with low (250 cc/hour) consumption of liquid He.Abstract:
The basic theories of Nuclear Quadrupole Resonance are outlined,
together with some basic NMR theory and its application to double resonance
techniques.
An improved design of spectrometer using double resonance is presented,
including a description of a new flow cryostat which can operate
down to 4.2°K with low (250 cc/hour) consumption of liquid He. The whole
apparatus may be used to detect NQR signals in solids over the frequency
range 100 kHz-5 MHz.
The theory of double resonance with spin mixing by continuous
coupling (D R CC) is developed and illustrated by experiments performed on
HCOOD, HDO and several nitrogen-containing compounds, including Imidazole.
Further experiments were then carried out on samples dilute in deuterium,
including the detection of NQR in formic acid (HCOOH) due to naturally
abundant deuterium. Other experiments on proton-deuteron interactions in
amide groups and in water molecules are also described and compared with
results previously published on fully-deuterated amides and D20 as a water
of crystallisation in L-serine hydrate.
The NQR spectrum of Lanthanum Nicotinate Dihydrate is obtained
using F.M. techniques and related to its structure.
The theory of Zeeman NQR in spin 3/2 nuclei is developed with
reference to the double resonance technique, and the measured quadrupole
coupling constants of 23Na and 2D in NaOH and some of its hydrates are
discussed.
Finally, some standard theories concerning proton relaxation times
in solids at low temperatures (4°K-300°K) are outlined and related to some,
measured relaxation times, illustrating their significance to the double
resonance technique.
The concluding chapter outlines a speculative proposal for a new
spectrometer design.read more
Citations
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BookDOI
Biophysical techniques in photosynthesis
Jan Amesz,Arnold J. Hoff +1 more
TL;DR: In this article, the photoacoustic method in photosynthesis - Monitoring and analysis of Phenomena which Lead to Pressure Changes Following Light Excitation S.J. Hoff and P.M. Small.
Journal ArticleDOI
Applications of nuclear quadrupole resonance spectroscopy in drug development.
TL;DR: This review covers different aspects of the use of NQR spectroscopy for drug development and analysis and illustrates the power and versatility of this method in the determination of impurities, polymorphic forms, the drug’s structure and conformation, characterization of the interactions between the drug and ligands, search for analogs and the drug's thermal stability.
Applications of Atomic Magnetometry and Hyperpolarized Xenon
TL;DR: In this article, a low-field detection of nuclear quadrupole resonance (NQR), J-coupling, and hyperpolarized xenon (hp-Xe) is described.
Journal ArticleDOI
Measurement of dipolar structure of 17O nuclear quadrupole resonance lines by three-frequency irradiation.
TL;DR: A modification of nuclear quadrupole double resonance with coupled multiplet is proposed which can be used for the measurement of the dipolar structure of the 17O nuclearquadrupole resonance lines in case of a strong 1H--17O dipolar interaction.
Journal ArticleDOI
Design of a minimal di-nickel hydrogenase peptide
Joshua A. Mancini,Douglas H. Pike,Saroj Poudel,Jennifer Timm,Alexei M. Tyryshkin,Jan Siess,Paul M. Molinaro,James J. McCann,Kate M. Waldie,Ronald L. Koder,Paul G. Falkowski,Vikas Nanda +11 more
TL;DR: A 13 amino acid nickel-binding peptide capable of robustly producing molecular hydrogen from protons under a wide variety of conditions is designed, demonstrating that modern enzymes, despite their enormous complexity, likely evolved from simple peptide precursors on early Earth.
References
More filters
BookDOI
Biophysical techniques in photosynthesis
Jan Amesz,Arnold J. Hoff +1 more
TL;DR: In this article, the photoacoustic method in photosynthesis - Monitoring and analysis of Phenomena which Lead to Pressure Changes Following Light Excitation S.J. Hoff and P.M. Small.
Journal ArticleDOI
Applications of nuclear quadrupole resonance spectroscopy in drug development.
TL;DR: This review covers different aspects of the use of NQR spectroscopy for drug development and analysis and illustrates the power and versatility of this method in the determination of impurities, polymorphic forms, the drug’s structure and conformation, characterization of the interactions between the drug and ligands, search for analogs and the drug's thermal stability.
Applications of Atomic Magnetometry and Hyperpolarized Xenon
TL;DR: In this article, a low-field detection of nuclear quadrupole resonance (NQR), J-coupling, and hyperpolarized xenon (hp-Xe) is described.
Journal ArticleDOI
Measurement of dipolar structure of 17O nuclear quadrupole resonance lines by three-frequency irradiation.
TL;DR: A modification of nuclear quadrupole double resonance with coupled multiplet is proposed which can be used for the measurement of the dipolar structure of the 17O nuclearquadrupole resonance lines in case of a strong 1H--17O dipolar interaction.
Proceedings ArticleDOI
New approaches to ultrasensitive magnetic resonance
Clifford R. Bowers,Steve K. Buratto,P. J. Carson,H. M. Cho,J. Y. Hwang,Leonard J. Mueller,Pedro J. Pizarro,David N. Shykind,Daniel P. Weitekamp +8 more
TL;DR: In this article, the authors describe several novel approaches to magnetic resonance, which have in common that the spins are coupled to other degrees of freedom in order to obtain nonequilibrium polarization and/or greater detection sensitivity.