Nutritional methods in the European Prospective Investigation of Cancer in Norfolk
Sheila Bingham,Ailsa A Welch,Alison McTaggart,Angela A. Mulligan,Shirley A. Runswick,Robert Luben,Suzy Oakes,Kay-Tee Khaw,Nicholas J. Wareham,Nicholas E. Day +9 more
Reads0
Chats0
TLDR
The food-frequency questionnaire (FFQ) and the food diary were able to determine differences in foods and nutrients between the sexes and were reliable as judged by repeated administrations of each method, particularly in men.Abstract:
Objective: To describe methods and dietary habits of a large population cohort. Design: Prospective assessment of diet using diet diaries and food-frequency questionnaires, and biomarkers of diet in 24-h urine collections and blood samples. Setting: Free living individuals aged 45 to 75 years living in Norfolk, UK. Subjects: Food and nutrient intake from a food-frequency questionnaire on 23 003 men and women, and from a 7-day diet diary from 2117 men and women. Nitrogen, sodium and potassium excretion was obtained from single 24-h urine samples from 300 individuals in the EPIC cohort. Plasma vitamin C was measured for 20 846 men and women. Results: The food-frequency questionnaire (FFQ) and the food diary were able to determine differences in foods and nutrients between the sexes and were reliable as judged by repeated administrations of each method. Plasma vitamin C was significantly higher in women than men. There were significant OP , 0:001U differences in mean intake of all nutrients measured by the two different methods in women but less so in men. The questionnaire overestimated dairy products and vegetables in both men and women when compared with intakes derived from the diary, but underestimated cereal and meat intake in men. There were some consistent trends with age in food and nutrient intakes assessed by both methods, particularly in men. Correlation coefficients between dietary intake assessed from the diary and excretion of nitrogen and potassium in a single 24-h urine sample ranged from 0.36 to 0.47. Those comparing urine excretion and intake assessed from the FFQ were 0.09 to 0.26. The correlations between plasma vitamin C and dietary intake from the first FFQ, 24-h recall or diary were 0.28, 0.35 and 0.40. Conclusions: EPIC Norfolk is one of the largest epidemiological studies of nutrition in the UK and the largest on which plasma vitamin C has been obtained. Methods for obtaining food and nutrient intake are described in detail. The results shown here for food and nutrient intakes can be compared with results from other population studies utilising different methods of assessing dietary intake. The utility of different methods used in different settings within the main EPIC cohort is described. The FFQ is to be used particularly in pooled analyses of risk from diet in relation to cancer incidence within the larger European EPIC study, where measurement error is more likely to be overcome by large dietary heterogeneity on an international basis. Findings in the UK, where dietary variation between individuals is smaller and hence the need to use a more accurate individual method greater, will be derived from the 7-day diary information on a nested case‐control basis. 24-h recalls can be used in the event that diary information should not be forthcoming from some eventual cases. Combinations of results utilising all dietary methods and biomarkers may also be possible.read more
Citations
More filters
Journal Article
Páginas de Salud Pública. Food, nutrition and the prevention of cancer: A global perspective. Conocimientos actuales sobre nutrición
Journal ArticleDOI
Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial
Lucilla Poston,Ruth Bell,Helen Croker,Angela C. Flynn,Keith M. Godfrey,Louise M Goff,Louise Hayes,Nina Khazaezadeh,Scott M. Nelson,Eugene Oteng-Ntim,Dharmintra Pasupathy,Nashita Patel,Stephen C. Robson,Jane Sandall,Thomas A. B. Sanders,Naveed Sattar,Paul T. Seed,Jane Wardle,Melissa Whitworth,Annette Briley +19 more
TL;DR: The primary outcomes did not differ between groups, despite improvements in some maternal secondary outcomes in the intervention group, including reduced dietary glycaemic load, gestational weight gain, and maternal sum-of-skinfold thicknesses, and increased physical activity.
Journal ArticleDOI
EPIC-Oxford: lifestyle characteristics and nutrient intakes in a cohort of 33 883 meat-eaters and 31 546 non meat-eaters in the UK.
Gwyneth K. Davey,Elizabeth A Spencer,Paul N. Appleby,Naomi E. Allen,Katherine H Knox,Timothy J. Key +5 more
TL;DR: Comparisons of the diet groups show wide ranges in the intakes of major nutrients such as saturated fat and dietary fibre, which should increase the ability of the study to detect associations of diet with major cancers and causes of death.
Journal ArticleDOI
Are imprecise methods obscuring a relation between fat and breast cancer
TL;DR: Dietary measurement error might explain the absence of a significant association between dietary fat and breast-cancer risk in cohort studies.
Journal ArticleDOI
Diet and cancer — the European Prospective Investigation into Cancer and Nutrition
Sheila Bingham,Elio Riboli +1 more
TL;DR: The European Prospective Investigation into Cancer and Nutrition — a study of over 500,000 people in 10 European countries — was devised, to investigate the relationship between diet, metabolic and genetic factors, and cancer.
References
More filters
Book
The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today
Richard Doll,Richard Peto +1 more
TL;DR: Evidence that the various common types of cancer are largely avoidable diseases is reviewed, and it is suggested that, apart from cancer of the respiratory tract, the types of cancers that are currently common are not peculiarly modern diseases and are likely to depend chiefly on some long-established factor.
Book
The dietary and nutritional survey of British adults.
TL;DR: Background, purpose and research design methodology for the dietary record anthropometric measurements and blood pressure purpose and methodology collection and analysis of urine and blood samples response to survey and characteristics of interviewed sample.
Journal ArticleDOI
Comparison of dietary assessment methods in nutritional epidemiology: weighed records v . 24 h recalls, food-frequency questionnaires and estimated-diet records
Sheila Bingham,Caroline Gill,Ailsa A Welch,K. Day,Aedin Cassidy,Kay-Tee Khaw,M. J. Sneyd,Timothy J. Key,L. Roe,Nicholas E. Day +9 more
TL;DR: Comparisons between the average of the 16 d weighed records and the first presentation of each method indicated that food-frequency questionnaires were not appreciably better at placing individuals in the distribution of habitual diet than 24 h recalls, due partly to inaccuracies in the estimation of frequency of food consumption.
Journal Article
Páginas de Salud Pública. Food, nutrition and the prevention of cancer: A global perspective. Conocimientos actuales sobre nutrición
Journal ArticleDOI
Validation of dietary assessment methods in the UK arm of EPIC using weighed records, and 24-hour urinary nitrogen and potassium and serum vitamin C and carotenoids as biomarkers.
Sheila Bingham,Caroline Gill,Ailsa A Welch,Aedin Cassidy,Shirley A. Runswick,Suzy Oakes,Robert Lubin,David I. Thurnham,Timothy J. Key,Lynn Roe,Kay-Tee Khaw,Nicholas E. Day +11 more
TL;DR: Three methods (the 7-day diary, an improved FFQ, and the 24-hour recall) are used to assess diet and limited biomarker information amongst 200 UK EPIC participants supported the findings of the validation study.