Journal ArticleDOI
Obstructive Sleep Apnea
TLDR
The nature and consequences of upper-airway obstruction in adults during sleep has evolved considerably over the past two decades, and there is insufficient awareness of sleep apnea among physicians and the public at large.Abstract:
Our understanding of the nature and consequences of upper-airway obstruction in adults during sleep has evolved considerably over the past two decades. Sleep apnea — defined as repeated episodes of obstructive apnea and hypopnea during sleep, together with daytime sleepiness or altered cardiopulmonary function — is common.1 Epidemiologic studies estimate that the condition affects 2 to 4 percent of middle-aged adults.2 Only a small portion of the cases in this group of adults have been diagnosed; this is related to insufficient awareness of sleep apnea among physicians and the public at large.3 Definitions The manifestations of upper-airway closure during sleep . . .read more
Citations
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Journal ArticleDOI
2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Robert Fagard,Krzysztof Narkiewicz,Josep Redon,Alberto Zanchetti,Michael Böhm,Thierry Christiaens,Renata Cifkova,Guy De Backer,Anna F. Dominiczak,Maurizio Galderisi,Diederick E. Grobbee,Tiny Jaarsma,Paulus Kirchhof,Sverre E. Kjeldsen,Stéphane Laurent,Athanasios J. Manolis,Peter M. Nilsson,Luis M. Ruilope,Roland E. Schmieder,Per Anton Sirnes,Peter Sleight,Margus Viigimaa,Bernard Waeber,Faiez Zannad,Michel Burnier,Ettore Ambrosioni,Mark Caufield,Antonio Coca,Michael H. Olsen,Costas Tsioufis,Philippe van de Borne,José Luis Zamorano,Stephan Achenbach,Helmut Baumgartner,Jeroen J. Bax,Héctor Bueno,Veronica Dean,Christi Deaton,Çetin Erol,Roberto Ferrari,David Hasdai,Arno W. Hoes,Juhani Knuuti,Philippe Kolh,Patrizio Lancellotti,Aleš Linhart,Petros Nihoyannopoulos,Massimo F Piepoli,Piotr Ponikowski,Juan Tamargo,Michal Tendera,Adam Torbicki,William Wijns,Stephan Windecker,Denis Clement,Thierry C. Gillebert,Enrico Agabiti Rosei,Stefan D. Anker,Johann Bauersachs,Jana Brguljan Hitij,Mark J. Caulfield,Marc De Buyzere,Sabina De Geest,Geneviève Derumeaux,Serap Erdine,Csaba Farsang,Christian Funck-Brentano,Vjekoslav Gerc,Giuseppe Germanò,Stephan Gielen,Herman Haller,Jens Jordan,Thomas Kahan,Michel Komajda,Dragan Lovic,Heiko Mahrholdt,Jan Östergren,Gianfranco Parati,Joep Perk,Jorge Polónia,Bogdan A. Popescu,Zeljko Reiner,Lars Rydén,Yuriy Sirenko,Alice Stanton,Harry A.J. Struijker-Boudier,Charalambos Vlachopoulos,Massimo Volpe,David A. Wood +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI
2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
Journal ArticleDOI
2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
Giuseppe Mancia,Robert Fagard,Krzysztof Narkiewicz,Josep Redon,Alberto Zanchetti,Michael Böhm,Thierry Christiaens,Renata Cifkova,Guy De Backer,Anna Dominiczak,Maurizio Galderisi,Diederick E. Grobbee,Tiny Jaarsma,Paulus Kirchhof,Sverre E. Kjeldsen,Stephane Laurent,Athanasios J. Manolis,Peter M. Nilsson,Luis M. Ruilope,Roland E. Schmieder,Per Anton Sirnes,Peter Sleight,Margus Viigimaa,Bernard Waeber,Faiez Zannad +24 more
TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
Journal ArticleDOI
Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss
Paul Poirier,Thomas D. Giles,George A. Bray,Yuling Hong,Judith S. Stern,F. Xavier Pi-Sunyer,Robert H. Eckel +6 more
TL;DR: The available evidence of the impact of obesity on CVD is reviewed with emphasis on the evaluation of cardiac structure and function in obese patients and the effect of weight loss on the cardiovascular system.
2007 Guidelines for the Management of Arterial Hypertension The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European
Giuseppe Mancia,Anna F. Dominiczak,Robert Fagard,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Roland E. Schmieder,Alec Vahanian,John Camm,Veronica Dean,Kenneth Dickstein,Christian Funck-Brentano,José Luis Zamorano,Serap Erdine,Krzysztof Narkiewicz,Enrico Agabiti-Rosei,Lars H Lindholm,Peter M. Nilsson,Stamatis Adamopoulos,Jean-Michel Mallion,Athanasios J. Manolis,Josep Redon,Pieter A. Van Zwieten,Margus Viigimaa +23 more
TL;DR: Since 2003 considerable additional evidence on important issues related to diagnostic and treatment approaches to hypertension has become available and therefore updating of the previous guidelines has been found advisable.
References
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The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults
TL;DR: The prevalence of undiagnosed sleep-disordered breathing is high among men and is much higher than previously suspected among women, and is associated with daytime hypersomnolence.
Journal ArticleDOI
Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares
TL;DR: Five patients with severe obstructive sleep apnoea were treated with continuous positive airway pressure (CPAP) applied via a comfortable nose mask through the nares, which provides a pneumatic splint for the nasopharyngeal airway and is a safe, simple treatment for the obstructiveSleep apNoea syndrome.
Journal ArticleDOI
Mortality and apnea index in obstructive sleep apnea: experience in 385 male patients
TL;DR: In this article, the authors calculated cumulative survival in 385 male obstructive sleep apnea patients and found that those with an apnea index (AI) greater than 20 had a much greater mortality than those with AI = less than 20.
Journal ArticleDOI
Objective Measurement of Patterns of Nasal CPAP Use by Patients with Obstructive Sleep Apnea
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TL;DR: Although the majority (60%) of patients claimed to use CPAP nightly, only 16 of 35 patients met criteria for regular use, defined by at least 4 h of CPAP administered on 70% of the days monitored, and these 16 patients had more years of education, and were more likely to work in professional occupations.
Journal ArticleDOI
A Cause of Excessive Daytime Sleepiness: The Upper Airway Resistance Syndrome
TL;DR: In this article, a group of diese subjects was investigated during nocturnal sleep and daytime naps, and sleep was fragmented by very short alpha EEC arousals throughout the sleeping period.