Offspring sex ratio of subfertile men and men with abnormal sperm characteristics
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This study of the reproduction of men who had a semen analysis at the Sperm Analysis Laboratory in Copenhagen in the period 1963-1993 showed that the subfertile men had an offspring sex ratio as expected, and within the cohort, the offspring sex ratios had no material association with particular semen characteristics.Abstract:
Previous work has suggested an association between male subfertility and a female-biased offspring sex ratio. This study of the reproduction of men who had a semen analysis at the Sperm Analysis Laboratory in Copenhagen in the period 1963-1993 showed that the subfertile men had an offspring sex ratio as expected (51.0% boys versus 51.3%, P: = 0.56), and within the cohort, the offspring sex ratio had no material association with particular semen characteristics. Our results thus suggest that no important association exists between general male subfertility and a female-biased offspring sex ratio.read more
Citations
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Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conception
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References
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Evidence for decreasing quality of semen during past 50 years.
TL;DR: There has been a genuine decline in semen quality over the past 50 years, and as male fertility is to some extent correlated with sperm count the results may reflect an overall reduction in male fertility.
Journal ArticleDOI
Evidence for Decreasing Quality of Semen During Past 50 Years
TL;DR: There has been a genuine decline in semen quality over the past 50 years and as male fertility is to some extent correlated with sperm count the results may reflect an overall reduction in male fertility.
Journal ArticleDOI
Risk of testicular cancer in subfertile men: case-control study
Henrik Møller,Niels E. Skakkebæk +1 more
TL;DR: Data are consistent with the hypothesis that male subfertility and testicular cancer share important aetiological factors, and were not influenced by adjustment for potential confounding factors.
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Change in male:female ratio among newborn infants in Denmark.
TL;DR: A dilemma is arrived at: although it may seem unethical to include patients in drug trials, such as CAST and SWORD, for fear of recording more deaths in the treatment arm, failure to conduct such studies would result in many patients being continually prescribed antiarrhythmic agents which may, because of their unspecified proarrhythmmic potential, cause death.
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Trends in sex-ratio, testicular cancer and male reproductive hazards: are they connected?
TL;DR: It is proposed as a hypothesis that there may exist common aetiological factors for testicular cancer, low fertility and low offspring sex-ratio, and that a search for the causal factors involved may focus on agents that can act prenatally to disrupt the normal development and differentiation of the male reproductive organs.