Journal ArticleDOI
On the occurrence of α-tocopherolquinone in rat tissue
John G. Bieri,Teresa J. Tolliver +1 more
TLDR
The amount of α-tocopherolquinone in rat liver has been reinvestigated comparing a conventional procedure including saponification and thin layer chromatography followed by high peformance liquid chromatography with the direct HPLC analysis of a total lipid extract.Abstract:
The amount of α-tocopherolquinone in rat liver has been reinvestigated comparing (a) a conventional procedure including saponification and thin layer chromatography followed by high peformance liquid chromatography (HPLC), with (b) the direct HPLC analysis of a total lipid extract. Recovery of added α-tocopherolquinone was quantitative with both procedures. In contrast to a recent report of 124 nmol/g in rat liver, we found no more than 1–4 nmol/g by procedure a and less than 1 nmol/g by procedure b.read more
Citations
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Journal ArticleDOI
Occurrence, biosynthesis and function of isoprenoid quinones.
Beatrycze Nowicka,Jerzy Kruk +1 more
TL;DR: Biosynthetic pathway of isoprenoid quinones has been described, as well as their additional, recently recognized, diverse functions in bacterial, plant and animal metabolism.
Journal ArticleDOI
The role of metabolism in the antioxidant function of vitamin E.
TL;DR: The antioxidant chemistry of alpha-tocopherol is described and the experimental evidence for the linkage ofalpha-tocopherylhydroquinone turnover to cellular metabolism through redox cycles is evaluated.
Journal ArticleDOI
Lipid analysis by thin-layer chromatography-A review of the current state
TL;DR: The combination betweenHPTLC and mass spectrometric (MS) detection methods will be discussed and it will be shown that this is a very powerful method to investigate the identities of the HPTLC spots in more detail than by the use of common staining methods.
Journal ArticleDOI
Modulation of antioxidant compounds in organic vs conventional fruit (peach, Prunus persica L., and pear, Pyrus communis L.).
TL;DR: Evidence is provided that an improvement in the antioxidant defense system of the plant occurred as a consequence of the organic cultivation practice, likely to exert protection against damage of fruit when grown in the absence of pesticides.
Book ChapterDOI
Biosynthesis of Ubiquinone
Robert E. Olson,Harry Rudney +1 more
TL;DR: This chapter discusses the biosynthesis of ubiquinone, which serves as a lipid-soluble electron carrier in the membrane-bound electron transport chains of both prokaryotes and eukaryotes.
References
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Journal ArticleDOI
Simultaneous determination of alpha-tocopherol and retinol in plasma or red cells by high pressure liquid chromatography.
TL;DR: Compared with conventional methods for these vitamins, the rapid, microprocedure for the simultaneous determination of alpha-tocopherol and retinol in plasma and alone in red cells gave excellent agreement with conventional Methods.
Book
Vitamin E: A Comprehensive Treatise
TL;DR: In this article, the biochemical, nutritional, physiological and pharmacological effects of the essential nutrient, Vitamin E, are presented in a comprehensive reference, including the history, nutrient functions, food sources, and metabolic and clinical roles of Vitamin E and its tocopherol and tocotrienol derivatives.
Journal ArticleDOI
Studies on vitamin E. 4. The simultaneous determinations of tocopherols, ubiquinones and ubichromenols (substance SC) in animal tissues: a reconsideration of the Keilin-Hartree heart preparation.
Journal ArticleDOI
Synthesis of alpha-tocopherolquinone by the rat and its reduction by mitochondria.
P E Hughes,S B Tove +1 more
TL;DR: In the presence of beta-hydroxybutyrate, pyruvate, succinate, succinated, and NADH, alpha-tocopherolquinone was reduced to alpha-ocopherol quinone by liver mitochondria, and it is likely that the reduction was not inhibited by rotenone or antimycin A, and not part of the classical mitochondrial electron transport system.
Related Papers (5)
Vitamin E: application of the principles of physical organic chemistry to the exploration of its structure and function
G. W. Burton,Keith U. Ingold +1 more