Journal ArticleDOI
Oophoropexy: a means of preserving ovarian function following pelvic megavoltage radiotherapy for Hodgkin's disease.
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Oophoropexy—placing both ovaries with their attached pedicles in the midline of the pelvis and marking their positions with metallic clips—was performed in 22 patients undergoing pelvic irradiation for Hodgkin's disease.Abstract:
Oophoropexy—placing both ovaries with their attached pedicles in the midline of the pelvis and marking their positions with metallic clips—was performed in 22 patients undergoing pelvic irradiation for Hodgkin's disease. Ovarian function was preserved in 12; 1 has conceived. The midline position of the ovaries allows them to be shielded with lead blocks during irradiation without interfering with treatment to the external iliac, obturator, or hypogastric nodes.read more
Citations
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Ionizing Radiation: Sources and Biological Effects
TL;DR: In this paper, the authors present an Ionizing Radiation Sources and Biological Effects (IRBE) study, in which the sources and biological effects of ionizing radiation are investigated and compared.
Journal ArticleDOI
Breast Cancer Following Radiotherapy and Chemotherapy Among Young Women With Hodgkin Disease
Lois B. Travis,Deirdre A. Hill,Graça M. Dores,Mary Gospodarowicz,Flora E. van Leeuwen,Eric J. Holowaty,Bengt Glimelius,Martin Andersson,Tom Wiklund,Charles F. Lynch,Mars B. van 't Veer,Ingrid Glimelius,Hans H. Storm,Eero Pukkala,Marilyn Stovall,Rochelle E. Curtis,John D. Boice,Ethel S. Gilbert +17 more
TL;DR: Hormonal stimulation appears important for the development of radiation-induced breast cancer, as evidenced by the reduced risk associated with ovarian damage from alkylating agents or radiation.
Journal ArticleDOI
Fertility preservation in female patients
Murat Sönmezer,Kutluk Oktay +1 more
TL;DR: A comprehensive algorithm to manage fertility preservation through an individualized approach is presented and all current, emerging, experimental as well as controversial approaches are reviewed.
Journal ArticleDOI
Gonadal damage from chemotherapy and radiotherapy.
Simon J Howell,Stephen M Shalet +1 more
TL;DR: Currently, sperm banking remains the only proven method in men, although hormonal manipulation to enhance the recovery of spermatogenesis and cryopreservation of testicular germ cells are possibilities for the future.
Journal ArticleDOI
Female Reproductive Potential after Treatment for Hodgkin's Disease
TL;DR: Even after intensive treatment programs, women successfully treated for Hodgkin's disease have become pregnant and delivered phenotypically normal children.
References
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Journal ArticleDOI
The value of laparotomy and splenectomy in the staging of Hodgkin's disease.
TL;DR: It is concluded that laparotomy with splenectomy is a valuable procedure for the more precise delineation of intra‐abdominal sites of involvement in Hodgkin's disease prior to the initiation of extended field megavoltage radiation therapy with curative intent.
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Physical and dosimetric aspects of the radiotherapy of malignant lymphomas. I. The mantle technique.
TL;DR: The skin and shielded lung doses received by the patients were investigated, and possible improvements are discussed, and the dosimetry method is efficient and rapid and yields acceptable uniformity of dose.
Journal Article
Approaches to improving the chemotherapy of Hodgkin's disease.
TL;DR: In preliminary studies combination chemotherapy produces an “additive” increase in the objective response, particularly the complete response, rate, and the implications of these studies and proposed extensions are presented.
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Castration1 of the Female by Irradiation
TL;DR: A study of patients with benign pelvic lesions was begun with the following objectives: determination of the efficiency of castration by radiation methods, establishment of the required ovarian dose for permanent castration, and development of a treatment technic to deliver a known and constable treatment.
Journal ArticleDOI
Exteriorization of ovaries under the skin of young women operated upon for cancer of the cervix.
TL;DR: Outsideization of the ovaries under the skin has been carried out with retention of the circulation through the ovarian vessels and in one case corpus luteum was found in an ovary removed 5 years after exteriorization.