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Optimization of custom cementless stem using finite element analysis and elastic modulus distribution for reducing stress-shielding effect.

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TLDR
Stress-shielding effect, measured as difference between the von Mises stress in the intact and implanted femur, decreased as the elastic modulus distribution is optimized.
Abstract
This work proposes a methodology involving stiffness optimization for subject-specific cementless hip implant design based on finite element analysis for reducing stress-shielding effect. To assess the change in the stress-strain state of the femur and the resulting stress-shielding effect due to insertion of the implant, a finite element analysis of the resected femur with implant assembly is carried out for a clinically relevant loading condition. Selecting the von Mises stress as the criterion for discriminating regions for elastic modulus difference, a stiffness minimization method was employed by varying the elastic modulus distribution in custom implant stem. The stiffness minimization problem is formulated as material distribution problem without explicitly penalizing partial volume elements. This formulation enables designs that could be fabricated using additive manufacturing to make porous implant with varying levels of porosity. Stress-shielding effect, measured as difference between the von Mises stress in the intact and implanted femur, decreased as the elastic modulus distribution is optimized.

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Citations
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Journal ArticleDOI

Enhanced Bone Remodeling Effects of Low-Modulus Ti-5Zr-3Sn-5Mo-25Nb Alloy Implanted in the Mandible of Beagle Dogs under Delayed Loading.

TL;DR: The TLM titanium alloy is considered a candidate implant material with desirable biomechanical compatibility, especially under applied stress, after fabricated by microarc oxidation followed by hydrothermal treatment.
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Load transfer and periprosthetic fractures after total hip arthoplasty: Comparison of periprosthetic fractures of femora implanted with cementless distal-load or proximal-load femoral components and measurement of the femoral strain at the time of implantation.

TL;DR: When proximal femoral strain was measured at the time of impaction of cementless stems the load transfer was determined by the underlying anatomy rather than by the shape of the stem, so that the so‐called “load transfer” properties ‐ proximal or distal ‐ ascribed to stem designs are a myth.

Développement d'une tige fémorale biomimétique intégrant une structure cellulaire poreuse

Bruno Jetté
TL;DR: In this article, deux articles scientifiques sont presentes en abordant l'elaboration and l'evaluation of the concept of tige femorale integrant a structure poreuse ordonnee.

3D Topology Optimization and Mesh Dependency for Redesigning Locking Compression Plates Aiming to Reduce Stress Shielding.

TL;DR: In this paper, the authors explored the use of three dimensional topology-optimization, based on compliance (i.e., strain energy) minimization, reshaping the design domain of three locking compression plates (four-screw holes, six screw holes, and eight screw holes), considering different volume reductions and loading conditions (bending, compression, torsion, and combined loads).
Journal ArticleDOI

Finite element analysis on the hollow porous design at the proximal end of cementless femoral prosthesis stem

TL;DR: The position and direction of hollow holes influenced the conducting force in holes but had no influence on stress values of femoral inner walls.
References
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Journal ArticleDOI

Material interpolation schemes in topology optimization

TL;DR: In this article, the authors analyze and compare the various approaches to this concept in the light of variational bounds on effective properties of composite materials, and derive simple necessary conditions for the possible realization of grey-scale via composites, leading to a physical interpretation of all feasible designs as well as the optimal design.
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Hip contact forces and gait patterns from routine activities.

TL;DR: The paper focuses on the loading of the femoral implant component but complete data are additionally stored on an associated compact disc that contains complete gait and hip contact force data as well as calculated muscle activities during walking and stair climbing and the frequencies of daily activities observed in hip patients.
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The relationship between stress shielding and bone resorption around total hip stems and the effects of flexible materials

TL;DR: The methods presented in this paper can be used to establish optimal stem-design characteristics or check the adequacy of designs in preclinical testing procedures.
Journal ArticleDOI

Mechanotransduction and the functional response of bone to mechanical strain

TL;DR: Mechanotransduction plays a crucial role in the physiology of many tissues including bone and some hormones may interact with local mechanical signals to change the sensitivity of the sensor or effector cells to mechanical load.
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Ten-year follow-up study of total hip replacement.

TL;DR: This series probably represents a so-called worst-case experience, since changes in design and materials as well as the improvements in surgical technique that have evolved over the past decade should provide significantly better long-term fixation.
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