Journal ArticleDOI
Origin of undifferentiated neoplasm from verrucous epidermal carcinoma of oral cavity following irradiation
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It is proposed that the anaplastic lesion of an x‐irradiated verrucous carcinoma of the oral cavity arose as a new carcinoma from the cells of the latter, rather than through a transformative dedifferentiation.Abstract:
Apparent anaplastic transformation of an x‐irradiated verrucous carcinoma of the oral cavity is described in detail, including ultrastructural observations. The anaplastic lesion had definite epidermoid differentiation in the form of tonofibrils and tonofilaments, demonstrable only with electron microscopy. It and the well‐differentiated one coexisted discretely and metastasized independently. It is proposed that the former arose as a new carcinoma from the cells of the latter, rather than through a transformative dedifferentiation.read more
Citations
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Journal ArticleDOI
Problems of verrucose squamous carcinoma.
Journal ArticleDOI
Radiotherapy in the treatment of verrucous carcinoma of the head and neck
Morgan E. Tharp,Homayoon Shidnia +1 more
TL;DR: This review of seven patients who had verrucous carcinoma of the head and neck that was treated with irradiation shows local control in 71% of cases, and it is concluded that surgery should be used if the procedure has acceptable morbidity and irradiation can be used.
Journal ArticleDOI
Chemosurgery for Verrucous Carcinoma
Frederic E. Mohs,William J. Sahl +1 more
TL;DR: Chemosurgery is advocated as the treatment of choice for verrucous carcinoma because ablation, being microscopically monitored, is most likely to be complete and because maximal conservation of tissue is assured.
Journal ArticleDOI
Verrucous carcinoma of the larynx. A clinical and pathologic study of 10 cases
TL;DR: Ten new verrucous carcinomas of the larynx are reported, collected over an 11‐year period, one of which makes up approximately 1 to 2% of all laryngeal carcinomas.
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Is primary radiotherapy an appropriate option for the treatment of verrucous carcinoma of the head and neck
TL;DR: The literature on verrucous carcinoma of the head and neck was reviewed to analyse the use of primary radiation therapy in the treatment of this lesion, and results emphasize an overall local control rate and 6.7 per cent of true anaplastic transformation following irradiation.
References
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Journal ArticleDOI
Anaplastic transformation in verrucous carcinoma of the oral cavity after radiation therapy.
TL;DR: Although a large number of cases of squamous carcinoma of the oral cavity have been irradiated, the poor response of verrucous carcinoma to this particular method of treatment has ...
Journal ArticleDOI
Verrucous squamous carcinoma of the oral cavity.
TL;DR: The study of the cIinica1 and pathologic features, treatment, and prognosis of such oral cavity Iesions encountered at the Mayo CIinic is concerned.
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Verrucous squamous cell carcinoma of the oral cavity
TL;DR: It would appear unnecessary to perform neck dissection in patients with verrucous‐type oral tumors who have a history of chewing tobacco and poor oral hygiene, and radiation therapy should be used in advanced verrucal‐type lesions in which surgery is difficult or not feasible.