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Origin of undifferentiated neoplasm from verrucous epidermal carcinoma of oral cavity following irradiation

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TLDR
It is proposed that the anaplastic lesion of an x‐irradiated verrucous carcinoma of the oral cavity arose as a new carcinoma from the cells of the latter, rather than through a transformative dedifferentiation.
Abstract
Apparent anaplastic transformation of an x‐irradiated verrucous carcinoma of the oral cavity is described in detail, including ultrastructural observations. The anaplastic lesion had definite epidermoid differentiation in the form of tonofibrils and tonofilaments, demonstrable only with electron microscopy. It and the well‐differentiated one coexisted discretely and metastasized independently. It is proposed that the former arose as a new carcinoma from the cells of the latter, rather than through a transformative dedifferentiation.

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Journal ArticleDOI

Penile Verrucous Carcinoma

TL;DR: A 71-year-old man with a penile verrucous carcinoma presenting as a large cutaneous horn and a brief review of the relevant medical literature and methods of therapy is included.
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Radiotherapy and verrucous carcinoma of the oral cavity. A study of 107 cases.

TL;DR: One hundred and seven cases of oral verrucous carcinoma treated primarily with radiotherapy at Kasturba Hospital, Manipal, India between 1977 and 1987 were analysed concerning location within the oral cavity, clinical extent, and effectiveness of radiotherapy.
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Verrucous Carcinoma of the Larynx Management by Radiotherapy and Surgery

TL;DR: It is concluded that radiotherapy and surgery are equally effective in eradicating verrucous carcinoma, and the current therapeutic policy is to treat by surgical excision those smaller tumors which can be removed by conservation laryngectomy procedures, reserving radiotherapy for those large tumors which would require total laryngesis if treated surgically.
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Verrucous Carcinoma of the Penis: Retrospective Analysis of 32 Cases

TL;DR: This study analyzed retrospectively the followup of 32 patients treated by surgery, exclusive radiotherapy and neoadjuvant chemotherapy between 1972 and 1987 with verrucous carcinoma of the penis, finding no patient died or had recurrent verruCous penile carcinoma.
Journal ArticleDOI

Oral verrucous carcinoma: An analysis of 37 cases

TL;DR: In this article, a delineation of the clinical presentation of verrucous hyperplasia and the relation of habits to the occurrence of the lesion was clarified, and the connotation of the term verroucous hypplasia was discussed.
References
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Journal ArticleDOI

Verrucous carcinoma of the oral cavity.

Lauren V. Ackerman
- 01 Apr 1948 - 
Journal ArticleDOI

Anaplastic transformation in verrucous carcinoma of the oral cavity after radiation therapy.

TL;DR: Although a large number of cases of squamous carcinoma of the oral cavity have been irradiated, the poor response of verrucous carcinoma to this particular method of treatment has ...
Journal ArticleDOI

Verrucous squamous carcinoma of the oral cavity.

TL;DR: The study of the cIinica1 and pathologic features, treatment, and prognosis of such oral cavity Iesions encountered at the Mayo CIinic is concerned.
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Verrucous squamous cell carcinoma of the oral cavity

TL;DR: It would appear unnecessary to perform neck dissection in patients with verrucous‐type oral tumors who have a history of chewing tobacco and poor oral hygiene, and radiation therapy should be used in advanced verrucal‐type lesions in which surgery is difficult or not feasible.
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