Journal ArticleDOI
Orthogonal selectivity with cinnamic acids in 3-substituted benzofuran synthesis through C–H olefination of phenols
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TLDR
A palladium catalyzed intermolecular annulation of cinnamic acids and phenols has been achieved for the selective synthesis of 3-substituted benzofurans.About:
This article is published in Chemical Communications.The article was published on 2015-03-12. It has received 58 citations till now. The article focuses on the topics: Decarboxylation & Annulation.read more
Citations
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Journal ArticleDOI
Palladium-catalyzed benzofuran and indole synthesis by multiple C–H functionalizations
TL;DR: This review is focused on the current development in the field of benzofuran and indole synthesis using multiple C-H functionalization strategies.
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Cobalt(III)-Catalyzed Intramolecular Cross-Dehydrogenative C-H/X-H Coupling: Efficient Synthesis of Indoles and Benzofurans.
TL;DR: An efficient cobalt(III)-catalyzed intramolecular cross-dehydrogenative C-H/N-H coupling of ortho-alkenylanilines has been developed utilizing O2 as a terminal oxidant that tolerates various reactive functional groups and allows the synthesis of diverse indole derivatives in good to excellent yields.
Journal ArticleDOI
Traceless directing groups: a novel strategy in regiodivergent C-H functionalization.
TL;DR: The traceless directing groups serve as the most ideal chelation assisted strategy with a high degree of reactivity and selectivity without any requirement for additional steps for their removal.
Journal ArticleDOI
Regioselective Synthesis of Multisubstituted Furans via Copper-Mediated Coupling between Ketones and β-Nitrostyrenes
TL;DR: A copper-mediated intermolecular annulation of alkyl ketones and β-nitrostyrenes has been developed for the regioselective synthesis of multisubstituted furan derivatives in good yields.
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Transition Metal Promoted Cascade Heterocycle Synthesis through C-H Functionalization.
TL;DR: The aim is to separate, and then highlight, the true domino reactions initiated by C-H activation, compared to other example of C- H functionalization for heterocycle syntheses.
References
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Journal ArticleDOI
The heck reaction as a sharpening stone of palladium catalysis.
TL;DR: s, or keywords if they used Heck-type chemistry in their syntheses, because it became one of basic tools of organic preparations, a natural way to make organic preparations.
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On the Interpretation of Deuterium Kinetic Isotope Effects in C ? H Bond Functionalizations by Transition-Metal Complexes
Eric M. Simmons,John F. Hartwig +1 more
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A versatile catalyst for Heck reactions of aryl chlorides and aryl bromides under mild conditions.
Adam F. Littke,Gregory C. Fu +1 more
TL;DR: In the presence of Cy2NMe, Pd/P(t-Bu)3 serves as an exceptionally mild and versatile catalyst for Heck reactions of aryl chlorides and bromides, representing an advance over previously reported catalysts for these Heck coupling processes.