Journal ArticleDOI
Para-acyl-calix-arene based solid lipid nanoparticles (SLNs): a detailed study of preparation and stability parameters.
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TLDR
The study of the effects of short time thermal treatment revealed that the SLNs are not affected by one freezing-defreezing cycle and are stable at 100 degrees C in suspension and it is difficult to reconstitute the SLN suspensions after freeze-drying.About:
This article is published in International Journal of Pharmaceutics.The article was published on 2003-03-06. It has received 148 citations till now. The article focuses on the topics: Dynamic light scattering.read more
Citations
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Journal ArticleDOI
Solid lipid nanoparticles for parenteral drug delivery.
TL;DR: The biological activity of parenterally applied SLN and biopharmaceutical aspects such as pharmacokinetic profiles as well as toxicity aspects are reviewed.
Journal ArticleDOI
Recent Advances in Lipid Nanoparticle Formulations with Solid Matrix for Oral Drug Delivery
Surajit Das,Anumita Chaudhury +1 more
TL;DR: In this article, a review of lipid nanoparticles based on solid matrix has been conducted to improve the oral bioavailability of several drugs, especially lipophilic compounds, and the stability of the formulations might increase than other liquid nano-carriers due to the solid matrix.
Journal Article
Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives.
Melike Üner,Gülgün Yener +1 more
TL;DR: In this paper, the authors review types of solid lipid nanoparticles (SLN), principles of drug loading and models of drug incorporation, and the influence of PEG coating on particle size and surface characteristics.
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Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system.
TL;DR: The drug in vitro release behavior from NLC displayed biphasic drug release pattern with burst release at theInitial stage and prolonged release afterwards, and the successful control of release rate at the initial stage can be achieved by controlling OA content.
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Nanostructured lipid carriers system: Recent advances in drug delivery
TL;DR: The present review gives insights on the definitions and characterization of NLC as colloidal carriers including the production techniques and suitable formulations and its future perspective as a pharmaceutical carrier.
References
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Journal ArticleDOI
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.
TL;DR: Relevant issues for the introduction of SLN to the pharmaceutical market, such as status of excipients, toxicity/tolerability aspects and sterilization and long-term stability including industrial large scale production are discussed.
Journal ArticleDOI
Solid lipid nanoparticles: Production, characterization and applications
W. Mehnert,Karsten Mäder +1 more
TL;DR: An overview about the selection of the ingredients, different ways of SLN production and SLN applications, and the in vivo fate of the carrier are presented.
Journal ArticleDOI
Supported Membranes: Scientific and Practical Applications
TL;DR: Supporting lipid-protein bilayers form versatile models of low-dimensionality complex fluids, which can be used to study interfacial forces and wetting phenomena, and enable the design of phantom cells to explore the interplay of lock-and-key forces and universal forces for cell adhesion.
Journal ArticleDOI
Micropatterning fluid lipid bilayers on solid supports.
TL;DR: Lithographically patterned grids of photoresist, aluminum oxide, or gold on oxidized silicon substrates were used to partition supported lipid bilayers into micrometer-scale arrays of isolated fluid membrane corrals to create arrays of fluid membrane patches with differing compositions.
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Solid lipid nanoparticles: Production, characterization and applications
W. Mehnert,Karsten Mäder +1 more