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Journal ArticleDOI

Peroxisomes (microbodies and related particles).

C De Duve, +1 more
- 01 Apr 1966 - 
- Vol. 46, Iss: 2, pp 323-357
About: 
This article is published in Physiological Reviews.The article was published on 1966-04-01. It has received 1540 citations till now. The article focuses on the topics: Microbody.

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Citations
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Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases

Alugoju Phaniendra, +2 more
- 01 Jan 2015 - 
TL;DR: The free radicals induced oxidative stress has been reported to be involved in several diseased conditions such as diabetes mellitus, neurodegenerative disorders, cardiovascular diseases, cardiovascular disease, respiratory diseases, cataract development, rheumatoid arthritis and in various cancers.
Journal ArticleDOI

The cellular production of hydrogen peroxide

Alberto Boveris, +2 more
- 01 Jul 1972 - 
TL;DR: The cytochrome c peroxidase assay is suitable for use with subcellular fractions from tissue homogenates as well as with pure enzyme systems to measure H(2)O( 2) generation and can be made on the basis of the rates with the isolated fractions under physiological conditions.
Journal ArticleDOI

Oxidative stress and autophagy: the clash between damage and metabolic needs

Giuseppe Filomeni, +2 more
- 01 Mar 2015 - 
TL;DR: This review aims at providing novel insight into the regulatory pathways of autophagy in response to glucose and amino acid deprivation, as well as their tight interconnection with metabolic networks and redox homeostasis.
Journal ArticleDOI

CORRELATED MORPHOMETRIC AND BIOCHEMICAL STUDIES ON THE LIVER CELL I. Morphometric Model, Stereologic Methods, and Normal Morphometric Data for Rat Liver

Ewald R. Weibel, +3 more
- 01 Jul 1969 - 
TL;DR: Stereologic methods which allow efficient and reliable quantitative evaluation of sectioned liver tissue are presented and validity and applicability of the method are discussed, and the data are compared with available information from other studies.
Journal ArticleDOI

The large-scale separation of peroxisomes, mitochondria, and lysosomes from the livers of rats injected with triton WR-1339. Improved isolation procedures, automated analysis, biochemical and morphological properties of fractions.

Federico Leighton, +6 more
- 01 May 1968 - 
TL;DR: Improved, largely automated methods are described for the purification and analysis of peroxisomes, lysosomes, and mitochondria from the livers of rats injected with Triton WR-1339, making more conclusive and precise previous estimates of the biochemical and morphological properties of the three groups of cytoplasmic particles.
References
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Journal ArticleDOI

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

C. De Duve, +4 more
- 01 Aug 1955 - 
TL;DR: The results are shown to favour the ferryl ion structure, or an isomer of this structure, for the higher oxidation state, and theHigher oxidation state may provisionally be named ferrylmyoglobin.
Journal ArticleDOI

Wege des Wasserstoffs in der lebendigen Organisation

Th. Bücher, +1 more
- 23 Sep 1958 - 
TL;DR: In this paper, weitgehend die Entwicklung der Problematik der dynamischen Biochemie an den Fortschritt der Cytologie gebunden ist.
Journal ArticleDOI

Tissue fractionation studies. 18. Resolution of mitochondrial fractions from rat liver into three distinct populations of cytoplasmic particles by means of density equilibration in various gradients.

Henri Beaufay, +5 more
- 01 Jul 1964 - 
Journal ArticleDOI

Localization of acid phosphatase activity in hepatic lysosomes by means of electron microscopy

Edward Essner, +1 more
- 01 Apr 1961 - 
TL;DR: The sites of reaction product of acid phosphatase activity as visualized in electron micrographs are consistent with those seen in frozen sections studied by light microscopy, and indicate that the pericanalicular bodies of parenchymatous cells, the large spherical bodies of Kupffer cells, and the microbodies appearing after bilirubin infusion and lipofuscin granules belong to the class of cytoplasmic organelles called lysosomes by
Journal ArticleDOI

COMBINED BIOCHEMICAL AND MORPHOLOGICAL STUDY OF PARTICULATE FRACTIONS FROM RAT LIVER: Analysis of Preparations Enriched in Lysosomes or in Particles Containing Urate Oxidase, D-Amino Acid Oxidase, and Catalase

Pierre Baudhuin, +2 more
- 01 Jul 1965 - 
TL;DR: Six particulate preparations isolated from rat liver under different experimental conditions were analyzed biochemically and examined in the electron microscope to confirm the lysosomal nature of the pericanalicular dense bodies and demonstrate that the microbodies are the bearers of urate oxidase, catalase, and D-amino acid oxidation.
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Protein Measurement with the Folin Phenol Reagent

Oliver H. Lowry, +3 more
- 01 Nov 1951 - 

Biogenesis of peroxisomes.

P B Lazarow, +1 more
- 01 Jan 1985 - 

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

Paul B. Lazarow, +1 more
- 01 Jun 1976 - 

The large-scale separation of peroxisomes, mitochondria, and lysosomes from the livers of rats injected with triton WR-1339. Improved isolation procedures, automated analysis, biochemical and morphological properties of fractions.

Federico Leighton, +6 more
- 01 May 1968 - 

Biochemistry of peroxisomes

H. van den Bosch, +3 more
- 01 Jan 1992 -