Journal ArticleDOI
Peyer's patches: morphologic studies.
TLDR
The investigations reported in this paper were undertaken to provide information on the structure and ultrastructure, the histochemistry, and the cellular kinetics of rabbit Peyer's patches to help clarify the role of these organs in the ontogeny of the immune response.About:
This article is published in Cellular Immunology.The article was published on 1970-11-01. It has received 98 citations till now. The article focuses on the topics: Bursa of Fabricius & Cellular immunity.read more
Citations
More filters
Journal ArticleDOI
Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
TL;DR: In addition to metabolic differences, the anatomical, physiological, and biochemical differences in the gastrointestinal (G.I.) tract of the human and common laboratory animals can cause significant variation in drug absorption from the oral route.
Review article comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
TL;DR: In this article, anatomical, physiological, and biochemical differences in the gastrointestinal tract of the human and common laboratory animals can cause significant variation in drug absorption from the oral route, including metabolic differences.
Book ChapterDOI
Immunoglobulin A (IgA): molecular and cellular interactions involved in IgA biosynthesis and immune response.
Jiri Mestecky,Jerry R. McGhee +1 more
TL;DR: The impact of new information concerning IgA physiology on the immune system is discussed, which suggests that IgA should not be considered only as an isotype providing specific humoral protection of mucosal surfaces but as an integral component of the entire immune system.
Journal ArticleDOI
Epithelial Cell Specialization within Human Peyer's Patches: An Ultrastructural Study of Intestinal Lymphoid Follicles
Robert L. Owen,Albert L. Jones +1 more
TL;DR: The newly discovered epithelial cells contain multiple vesicles that suggest a transport function, possibly for luminal antigenic material or for secretory immunoglobulin, in human intestinal mucosal cell type M cells.
Journal ArticleDOI
Peyer's patches: an enriched source of precursors for iga-producing immunocytes in the rabbit
Susan W. Craig,John J. Cebra +1 more
TL;DR: Pyer's patches are a highly enriched source of cells which have the potential to proliferate and differentiate into IgA-producing immunocytes and are far more efficient in seeding the gut of irradiated recipient rabbits with donor cells that give rise to immunoglobulin-producing cells than cells from peripheral blood or popliteal lymph nodes.
References
More filters
Journal ArticleDOI
Histopathologic technic and practical histochemistry.
TL;DR: Histopathologies technic and practical histochemistry, Histopathologie techno-practical histochemistry and the role of nanofiltration in medicine and drug discovery and abuse are studied.
Journal ArticleDOI
Collagenolytic Activity in Amphibian Tissues: a Tissue Culture Assay
Jerome Gross,Charles M. Lapière +1 more
TL;DR: The model suggests that lipid plays an essential role and show that even substances which are not intrinsically surface active can have profound effects when the composition of the interfacial phase is suitably chosen, and further studies of its changes of physical state under narcotics may be very informative.
Journal ArticleDOI
The Route of Re-Circulation of Lymphocytes in the Rat
J. L. Gowans,E. J. Knight +1 more
TL;DR: It was concluded that the re-circulating pool of small lymphocytes was located in the lymphoid tissue, the thymus excepted, and that the rapid ‘homing’ of cells into the lymph nodes had its basis in the special affinity ofsmall lymphocytes for the endothelium of the post-capillary venules.
Journal ArticleDOI
The functions of the thymus system and the bursa system in the chicken
TL;DR: The bursa of Fabricius and the thymus are "central lymphoid organs" in the chicken, essential to the ontogenetic development of adaptive immunity in that species, and surgical removal of one or both of these organs has permitted recognition of two morphologically distinct cell systems in the "peripheral lymphoid tissues" of the spleen, gut, and other organs.
Journal ArticleDOI
The Bursa of Fabricius and Antibody Production
TL;DR: Although reticular cells of lymph glands and lymphocytes may participate in globulin and antibody synthesis (Raffel, 1953), suspicion regarding the importance of the bursa in antibody production arose in the following accidental manner.
Related Papers (5)
Epithelial Cell Specialization within Human Peyer's Patches: An Ultrastructural Study of Intestinal Lymphoid Follicles
Robert L. Owen,Albert L. Jones +1 more
Peyer's patches: an enriched source of precursors for iga-producing immunocytes in the rabbit
Susan W. Craig,John J. Cebra +1 more