Journal ArticleDOI
Preparation, Pharmacokinetics and Body Distribution of Silymarin-Loaded Solid Lipid Nanoparticles After Oral Administration
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This article is published in Journal of Biomedical Nanotechnology.The article was published on 2007-06-01. It has received 49 citations till now. The article focuses on the topics: Distribution (pharmacology) & Solid lipid nanoparticle.read more
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Journal ArticleDOI
Phospholipids and lipid-based formulations in oral drug delivery.
Gert Fricker,Torsten Kromp,Armin Wendel,Alfred Blume,Jürgen Zirkel,Herbert Rebmann,Constanze Setzer,Ralf-Olaf Quinkert,Frank Martin,Christel C. Müller-Goymann +9 more
TL;DR: In this article, the authors summarized particular features of commonly used phospholipids and their application spectrum within oral drug formulation and elucidates current strategies to improve bioavailability and disposition of orally administered drugs.
Journal Article
Reassessing bioavailability of silymarin.
TL;DR: This article critically reviews the recent published literature on various techniques for increasing the bioavailability of silymarin and describes an array of methods that can improve its bioavailability.
Journal ArticleDOI
Oil based nanocarrier for improved oral delivery of silymarin: In vitro and in vivo studies
TL;DR: The present study showed that the nanoemulsion being a versatile technology has the potential to improve the biopharmaceutics properties of silymarin.
Journal ArticleDOI
Topical ophthalmic lipid nanoparticle formulations (SLN, NLC) of indomethacin for delivery to the posterior segment ocular tissues.
TL;DR: The results suggest that lipid-based particulate systems can serve as viable vehicles for ocular delivery.
Journal ArticleDOI
Formulation Strategies for Enhancing the Bioavailability of Silymarin: The State of the Art.
TL;DR: To improve its bioavailability and provide a prolonged silymarin release at the site of absorption, the use of nanotechnological strategies appears to be a promising method to potentiate the therapeutic action and promote sustained release of the active herbal extract.
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W. Mehnert,Karsten Mäder +1 more