Journal ArticleDOI
Prevalence and types of glaucoma among an indigenous African population in southwestern Nigeria.
Adeyinka O. Ashaye,Olumide Ashaolu,Opeyemi O. Komolafe,Benedict G. K. Ajayi,Olusola Olawoye,Boluwatife Olusanya,C O Adeoti +6 more
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TLDR
The high prevalence of glaucoma in the Akinyele district in southwestern Nigeria is comparable with those in predominantly black populations in theAkwapim-South district of Ghana and Barbados.Abstract:
PURPOSE To determine the prevalence and identify the types of glaucoma in the Akinyele district of Oyo State in southwestern Nigeria. METHODS Residents of Akinyele district of Oyo State in southwestern Nigeria aged 40 years and older were randomly selected in a stratified manner. All participants underwent comprehensive ophthalmic examination, including visual acuity assessment, anterior segment biomicroscopy, IOP measurement, gonioscopy, optic nerve head and disc evaluation, and central visual field assessment. Glaucoma was diagnosed using the International Society of Geographical and Epidemiological Ophthalmology (ISGEO) classification scheme. RESULTS A sample of 811 subjects (90% response rate) was examined. The crude prevalence of all forms of glaucoma was 7.3% (95% confidence interval [CI] 5.5%-9.1%) with an age and sex standardized rate of 6.9% (95% CI 6.88%-6.92%). Primary open angle glaucoma was found in 6.2% (95% CI 4.5%-7.8%) and primary angle closure glaucoma in 0.2% (95% CI 0.0%-0.6%). Secondary glaucoma accounted for 0.9% of the cases, with couching and neovascular process being the main causes (0.2% each). Prevalence of glaucoma increased significantly with increasing age (P for trend < 0.05). CONCLUSIONS The high prevalence of glaucoma (7.3%) in the Akinyele district in southwestern Nigeria is comparable with those in predominantly black populations in the Akwapim-South district of Ghana and Barbados. Primary open angle glaucoma remains the most prevalent form of glaucoma.read more
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Journal Article
Global variations and time trends in the prevalence of primary open angle glaucoma: a systematic review and meta-analysis
Paul J. Foster,Paul J. Foster,Michelle P.Y. Chan,Venediktos V Kapetanakis,Christopher G. Owen,Alicja R. Rudnicka +5 more
TL;DR: This systematic review provides the most precise estimates of POAG prevalence and shows omitting routine visual field assessment in population surveys may have affected case ascertainment.
Journal ArticleDOI
A Population-based survey of the prevalence and types of glaucoma in Nigeria: results from the Nigeria National Blindness and Visual Impairment Survey.
Fatima Kyari,Fatima Kyari,Gabriel Entekume,Mansur M. Rabiu,Paul G. D. Spry,Richard Wormald,Richard Wormald,Winifred P. Nolan,Gudlavalleti V S Murthy,Gudlavalleti V S Murthy,Clare Gilbert +10 more
TL;DR: The Nigeria National Blindness and Visual Impairment cross-sectional Survey of adults aged ≥40 years is determined, finding that Nigeria has a high prevalence of glaucoma which is largely open-angle glAUcoma.
Journal ArticleDOI
Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review.
TL;DR: In this article, a meta-analysis was performed to determine the worldwide prevalence of primary open-angle glaucoma (POAG) in the adult general population for the last 20 years, and explore variation in prevalence by age, gender and geographical location.
Journal ArticleDOI
Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations
Ryan Zukerman,Alon Harris,Alice Chandra Verticchio Vercellin,Brent Siesky,Louis R. Pasquale,Thomas A. Ciulla +5 more
TL;DR: In this article, the authors synthesize the current literature on glaucoma and genetics, as stratified by the subtypes and ethnicity of primary open-angle (POAG) and exfoliation (XFG), and conclude that the unified molecular pathways accounting for POAG pathogenesis remain uncertain, although inflammation and senescence likely play an important role.
Journal ArticleDOI
Clinical Correlates of Computationally Derived Visual Field Defect Archetypes in Patients from a Glaucoma Clinic.
TL;DR: Shared clinical features between computationally derived VF Archetypes and clinically observed VF patterns support the clinical validity of VF archetypal analysis.
References
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Journal ArticleDOI
The number of people with glaucoma worldwide in 2010 and 2020
Harry A. Quigley,Aimee T. Broman +1 more
TL;DR: Glaucoma is the second leading cause of blindness worldwide, disproportionately affecting women and Asians, and it will be 60.5 million people with OAG and ACG in 2010, increasing to 79.6 million by 2020, and of these, 74% will have OAG.
Journal ArticleDOI
The definition and classification of glaucoma in prevalence surveys
TL;DR: This review describes a scheme for diagnosis of glaucoma in population based prevalence surveys that makes provision for diagnosing glauca in eyes with severe visual loss where formal field testing is impractical, and for blind eyes in which the optic disc cannot be seen because of media opacities.
Journal ArticleDOI
Racial variations in the prevalence of primary open-angle glaucoma. The Baltimore Eye Survey.
James M. Tielsch,Alfred Sommer,Joanne Katz,Richard M. Royall,Harry A. Quigley,Jonathan C. Javitt,Jonathan C. Javitt +6 more
TL;DR: Black Americans are at higher risk of primary open-angle glaucoma than their white neighbors, which may reflect an underlying genetic susceptibility to this disease and indicates that additional efforts are needed to identify and treat this sight-threatening disorder in high-risk communities.
Practical Issues in Calculating the Sample Size for Prevalence Studies
Lin Naing,T Winn +1 more
TL;DR: In this article, the sample size calculation for a prevalence only needs a simple formula and several practical issues in selecting values for the parameters required in the formula are addressed and appropriate recommendations are given.
Journal ArticleDOI
Prevalence of glaucoma. The Beaver Dam Eye Study.
Barbara E.K. Klein,Ronald Klein,William E. Sponsel,Todd Franke,Louis B. Cantor,James F. Martone,Mitchell J. Menage +6 more
TL;DR: The prevalence of open-angle glaucoma in Beaver Dam is similar to that in other white populations, and findings from this study re-emphasize the notion that estimates of glauca prevalence should be based on assessing multiple risk indicators.
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