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Journal ArticleDOI

Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.

TLDR
The global prevalence of primary open-angle glaucoma (POAG) and primary angle-closure glauComa (PACG) and the number of affected people in 2020 and 2040 are examined, disproportionally affecting people residing in Asia and Africa.
About
This article is published in Ophthalmology.The article was published on 2014-11-01. It has received 4318 citations till now. The article focuses on the topics: Population & Glaucoma.

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Journal ArticleDOI

Global Causes of Blindness and Distance Vision Impairment 1990-2020: A Systematic Review and Meta-Analysis

Seth Flaxman, +109 more
TL;DR: A series of regression models were fitted to estimate the proportion of moderate or severe vision impairment and blindness by cause, age, region, and year, and found that world regions varied markedly in the causes of blindness and vision impairment in this age group.
Journal ArticleDOI

Primary open-angle glaucoma.

TL;DR: Primary open-angle glaucoma (POAG) is the most common type and management of POAG includes topical drug therapies and surgery to reduce IOP, although new therapies targeting neuroprotection of RGCs and axonal regeneration are under development.
Journal ArticleDOI

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study.

TL;DR: Results suggest eye care services contributed to the observed reduction of age-standardised rates of avoidable blindness but not of MSVI, and that the target in an ageing global population was not reached.
Journal ArticleDOI

Artificial intelligence and deep learning in ophthalmology

TL;DR: There are also potential challenges with DL application in ophthalmology, including clinical and technical challenges, explainability of the algorithm results, medicolegal issues, and physician and patient acceptance of the AI ‘black-box’ algorithms.
Journal ArticleDOI

Joint Optic Disc and Cup Segmentation Based on Multi-Label Deep Network and Polar Transformation

TL;DR: Zhang et al. as discussed by the authors proposed a multi-scale input layer, U-shape convolutional network, side-output layer, and multi-label loss function for OD and OC segmentation.
References
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Journal ArticleDOI

Meta-analysis of observational studies in epidemiology - A proposal for reporting

TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI

The number of people with glaucoma worldwide in 2010 and 2020

TL;DR: Glaucoma is the second leading cause of blindness worldwide, disproportionately affecting women and Asians, and it will be 60.5 million people with OAG and ACG in 2010, increasing to 79.6 million by 2020, and of these, 74% will have OAG.
Journal ArticleDOI

Number of people with glaucoma worldwide.

TL;DR: Improved methods of screening and therapy for glaucoma are urgently needed, as it is the second leading cause of vision loss in the world.
Journal ArticleDOI

The definition and classification of glaucoma in prevalence surveys

TL;DR: This review describes a scheme for diagnosis of glaucoma in population based prevalence surveys that makes provision for diagnosing glauca in eyes with severe visual loss where formal field testing is impractical, and for blind eyes in which the optic disc cannot be seen because of media opacities.
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