Journal ArticleDOI
Psychic Disturbances in Adult Coeliac Disease
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TLDR
The concentrations of three major monoamine metabolites in samples of lumbar cerebrospinal fluid of ten consecutive adults with newly detected coeliac disease were inversely correlated with depressive symptoms reported on the MMPI scale 2, which conforms with current concepts on the pathogenesis of depression.Abstract:
Untreated adult coeliac patients have previously been shown to have a high frequency of depressive symptoms as reported in a personality inventory (the MMPI). In the present study we determined the concentrations of three major monoamine metabolites in samples of lumbar cerebrospinal fluid of ten consecutive adults with newly detected coeliac disease. They showed significant reduction in levels of 5-HIAA (70.3 ± 25.4 pmol/ml), HVA (128.2 ± 58.3 pmol/ml), and MOPEG (27.7 ± 7.4 pmol/ml), indicating reduced central metabolism in all three monoamine pathways. The concentrations, in particular that of MOPEG, were inversely correlated with depressive symptoms reported on the MMPI scale 2 (‘depression’), which conforms with current concepts on the pathogenesis of depression.read more
Citations
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Journal ArticleDOI
Neurologic presentation of celiac disease.
TL;DR: It has been suggested that gluten sensitivity (as evidenced by high antigliadin antibodies) is a common cause of neurologic syndromes (notably cerebellar ataxia) of otherwise unknown cause and further studies clearly are needed to assess the efficacy of gluten-free diet and to address the underlying mechanisms of nervous system pathology in gluten sensitivity.
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Intestinal Pathophysiology in Autism
TL;DR: The pathology, reported to extend from the esophagus to the colon, is described here along with other studies pointing to a connection between diet and the severity of symptoms expressed in autism.
Journal ArticleDOI
'Controlled by food'- lived experiences of coeliac disease.
TL;DR: The lived experiences of coeliac disease were more varied and profound than expected and it is important to take psychological and social aspects into account in the treatment of patients with coelacio disease.
Journal ArticleDOI
Follow-up of patients with celiac disease: achieving compliance with treatment.
TL;DR: An algorithm for the follow-up and management of the newly diagnosed celiac disease patient is presented, which includes regular follow- up; measurement of serum antibodies; eliciting a detailed dietary history; and examination for signs and symptoms of nutritional deficiencies, malignancy, and other autoimmune diseases.
Journal ArticleDOI
Quality of life of adult coeliac patients treated for 10 years
Claes Hallert,Christer Grännö,C. Grant,S. Hultén,G. Midhagen,Magnus Ström,H. Svensson,T. Valdimarsson,T. Wickström +8 more
TL;DR: Assessment of aspects of the quality of life of adult coeliac patients who had been on a GFD for 10 years found the functional status and perceived health of the coeliasis patients appeared unrelated to their biopsy find.
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