Journal ArticleDOI
Publication bias and clinical trials.
TLDR
It appears that nonpublication was primarily a result of failure to write up and submit the trial results rather than rejection of submitted manuscripts, implying the existence of a publication bias of importance both to meta-analysis and the interpretation of statistically significant positive trials.About:
This article is published in Controlled Clinical Trials.The article was published on 1987-12-01. It has received 638 citations till now. The article focuses on the topics: Publication bias & Randomized controlled trial.read more
Citations
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Journal ArticleDOI
Publication bias in clinical research
TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
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Quantitative Synthesis in Systematic Reviews
TL;DR: A stepwise description of the tasks that are performed when statistical methods are used to combine data and the question, Are the results of the different studies similar (homogeneous)?
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Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy
TL;DR: A systematic literature search found that among 74 FDA-registered studies, 31%, accounting for 3449 study participants, were not published, and the increase in effect size ranged from 11 to 69% for individual drugs and was 32% overall.
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Systematic Reviews: Identifying relevant studies for systematic reviews
TL;DR: Although the indexing terms available for searching Medline for randomised clinical trials have improved, sensitivity still remains unsatisfactory.
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The answer is 17 years, what is the question: understanding time lags in translational research:
TL;DR: This paper reviewed the literature describing and quantifying time lags in the health research translation process and concluded that the current state of knowledge of time lag is of limited use to those responsible for R&D and knowledge transfer who face difficulties in knowing what they should or can do to reduce time lag.
References
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Journal ArticleDOI
Meta-Analysis in Clinical Trials*
TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
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The file drawer problem and tolerance for null results
TL;DR: Quantitative procedures for computing the tolerance for filed and future null results are reported and illustrated, and the implications are discussed.
Book
Meta-analytic procedures for social research
TL;DR: In this paper, the authors define research results, retrieve and assess research results and compare and combine research results to combine probabilities, and evaluate meta-analytic procedures and meta-Analytic results.
Journal ArticleDOI
Primary, Secondary, and Meta-Analysis of Research
TL;DR: The meta-analysis of research as discussed by the authors is an important feature of the research and evaluation enterprise, and it has been widely used in the field of computer science and computer engineering, especially in the context of education.
Journal ArticleDOI
The combination of estimates from different experiments.
TL;DR: The problem of making a combined estimate has been discussed previously by Cochran and Yates and Cochran (1937) for agricultural experiments, and by Bliss (1952) for bioassays in different laboratories as discussed by the authors.