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Pulmonary carcinosarcoma with heterologous component: report of two cases with literature review

TLDR
Two cases of carcinosarcoma are reported in a 68-year-old patient and a 78-year old patient explored for lung masses, consisting in adenosquamous carcinoma with osteosarcomA in one case and adenocarcinoma with chondrosarcomas in the other case.
Abstract
Carcinosarcoma is an uncommon malignant biphasic tumor that accounts for less than 1% of all lung cancers. It is defined by coexisting histologic elements of carcinomatous and sarcomatous components. We report two cases of carcinosarcoma in a 68-year-old patient and a 78-year-old patient explored for lung masses. Macroscopically, the resected tumors were 7 and 10 cm in diameter. Histologically, they consisted in adenosquamous carcinoma with osteosarcoma in one case and adenocarcinoma with chondrosarcoma in the other case.

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Journal ArticleDOI

Pulmonary Carcinosarcoma: A Surveillance, Epidemiology, and End Results (SEER) Analysis.

TL;DR: Treatment with surgery alone resulted in superior survival outcomes compared to other treatment modality combinations, regardless of patient age and disease stage, within the limitations of this study.
Journal ArticleDOI

Pulmonary carcinosarcoma: analysis from the Surveillance, Epidemiology and End Results database.

TL;DR: PCS had unique clinical features compared to common types of NSCLCs in terms of lymphatic invasion and surgical treatment and was associated with a poorer outcome compared to lobectomy amongst the elderly patients.
Journal ArticleDOI

Sarcomatoid Carcinoma of the lung: A rare case of three small intestinal intussusceptions and literature review

TL;DR: This presentation shows the third case in literature of small intestinal intussusceptions caused by metastatic lung carcinosarcoma, a kind of tumor that is not active in medical treatment, chemotherapy, and radiotherapy.
Journal ArticleDOI

Sarcomatoid carcinoma of the lung mimics aspergilloma on ¹⁸F-FDG PET/CT.

TL;DR: A case of PSC with air crescent and halo signs that resemble aspergilloma on the ¹⁸F-FDG PET/CT, scan is presented.
Journal ArticleDOI

Key Features in the Management of Pulmonary Carcinosarcoma

TL;DR: The optimal management of patients with pulmonary carcinosarcoma is discussed by means of a case illustration and review of the literature, and the heterogeneity of the tumour is discussed.
References
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Journal ArticleDOI

Primary pulmonary sarcomas and carcinosarcomas--postoperative results and comparative survival analysis.

TL;DR: There is no significant difference in the survival rates between PPS and PCa Sa patients, despite the greater number of cases with higher stages in PCaSa group.
Journal ArticleDOI

Pulmonary carcinosarcoma: diagnostic problems and determinants of the prognosis.

TL;DR: The prognosis of carcinosarcoma of the lung is assessed to be comparable to that of patients with other pulmonary carcinoma: in this study survival times ranged from only 3 months (T2N3) to 4 years 6 weeks (T3N1).
Journal ArticleDOI

Pulmonary carcinosarcoma: radiologic and pathologic findings in three patients.

TL;DR: Three patients with pulmonary carcinosarcoma had tumors that measured 9-14 cm in diameter, had inhomogeneous contrast enhancement, and in two cases had invaded the mediastinum or chest wall extensively.
Journal ArticleDOI

Pulmonary carcinosarcoma initially presenting as invasive aspergillosis: a case report of previously unreported combination

TL;DR: A case of primary carcinosarcoma of the lung concurrently occurring with invasive pulmonary aspergillosis in a 66-year old patient is described.
Journal Article

A case of pulmonary carcinosarcoma (squamous cell carcinoma and osteosarcoma) treated with cisplatin and doxorubicin.

TL;DR: The aggressiveness of this rare tumor entity, its histological heterogeneity, and its potential coexistence with non-small cell lung cancer (NSCLC) make the management of patients with pulmonary carcinosarcoma a diagnostic and therapeutic challenge.
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