Journal ArticleDOI
Pulmonary Function Growth Velocity in Children 6 to 18 Years of Age
Xiaobin Wang,Douglas W. Dockery,David Wypij,Diane R. Gold,Frank E. Speizer,James H. Ware,Benjamin G. Ferris +6 more
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TLDR
There were considerable variations in the age of onset and magnitudes of the adolescent growth spurts of the pulmonary function parameters both between sexes and among children of the same sex.Abstract:
Pulmonary function growth rate varies with a child's stage of growth. Since attained pulmonary function reflects the cumulative effects of growth, insults, and repair, rate of growth may be a more sensitive indicator of a child's current pulmonary health status. The sample for analyses included 2,478 white boys and 2,785 white girls followed annually by questionnaire and spirometry. Empirically derived annual growth velocities, peak velocity (Vpk), and age at which peak velocity occurred (Agepk) were determined for height, FVC, FEV1, and FEF25–75 for each child. Mean velocity curves for height, FVC, FEV1, and FEF25–75, stratified by sex and Agepk of height (an indicator for early, middle, or late maturity) were produced as a function of age. The differences between Agepk of FVC, FEV1, and FEF25–75 and Agepk of height (i.e., the lag period) were compared by sex and by the indicator of maturity. Linear regression analyses were performed to investigate associations between Vpk and Agepk of height, as well as...read more
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Journal ArticleDOI
Spirometric Reference Values from a Sample of the General U.S. Population
TL;DR: Hankinson and Odencrantz as mentioned in this paper used a piecewise polynomial model with age and height as predictors to derive reference values for three race/ethnic groups and should prove useful for diagnostic and research purposes.
Journal ArticleDOI
The effect of air pollution on lung development from 10 to 18 years of age.
W. James Gauderman,Edward L. Avol,Frank D. Gilliland,Hita Vora,Duncan C. Thomas,Kiros Berhane,Rob McConnell,Nino Kuenzli,Fred Lurmann,Edward B. Rappaport,Helene G. Margolis,David W. Bates,John M. Peters +12 more
TL;DR: Current levels of air pollution have chronic, adverse effects on lung development in children from the age of 10 to 18 years, leading to clinically significant deficits in attained FEV as children reach adulthood.
Journal ArticleDOI
Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study
W. James Gauderman,Hita Vora,Rob McConnell,Kiros Berhane,Frank D. Gilliland,Duncan C. Thomas,Fred Lurmann,Edward L. Avol,Nino Künzli,Michael Jerrett,John M. Peters +10 more
TL;DR: In this paper, the authors investigated the association between residential exposure to traffi c and 8-year lung function growth and found that children who lived within 500 m of a freeway (motorway) had substantial defi cits in 8 years growth of forced expiratory volume in 1 s (FEV1, −81 mL, p=0·01 [95% CI −143 to −18]) and maximum midexpiratory fl ow rate (MMEF, −127 mL/s, p =0·03 [−243 to −11
Journal ArticleDOI
Gender differences in airway behaviour over the human life span
TL;DR: Physiologists have in general paid more attention than clinicians to gender differences in airway behaviour, even though gender differences are an important determinant of the clinical manifestations of airway disease.
Journal ArticleDOI
Effects of Cigarette Smoking on Lung Function in Adolescent Boys and Girls
TL;DR: Whereas girls who did not smoke reached a plateau of lung function at 17 to 18 years of age, girls of the same age who smoked had a decline of FEV1 and FEF25-75, and adolescent girls may be more vulnerable than boys to the effects of smoking on the growth of lungfunction.
References
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Journal ArticleDOI
Robust Locally Weighted Regression and Smoothing Scatterplots
TL;DR: Robust locally weighted regression as discussed by the authors is a method for smoothing a scatterplot, in which the fitted value at z k is the value of a polynomial fit to the data using weighted least squares, where the weight for (x i, y i ) is large if x i is close to x k and small if it is not.
Journal ArticleDOI
Clinical longitudinal standards for height and height velocity for North American children
James M. Tanner,Peter Davies +1 more
TL;DR: Longitudinally-based height and height velocity charts for North American children are presented, suitable for following an individual child's progress during observation or treatment throughout the growth period, including puberty.
Journal ArticleDOI
Pulmonary function between 6 and 18 years of age.
TL;DR: Race‐, sex‐, and age‐specific regression equations based on height are provided, which permit the evaluation of growth during adolescence with improved accuracy and, more importantly, in comparison with previous observations for the same child.
Journal ArticleDOI
Distribution of forced vital capacity and forced expiratory volume in one second in children 6 to 11 years of age.
TL;DR: Sex- and race-specific lung function development is described for this sample of preadolescent children, and regression analysis showed that height, race, and sex are the most important predictors of lung function.
Journal ArticleDOI
Longitudinal height velocity standards for U.S. adolescents
TL;DR: Longitudinally based height velocity centiles for U.S. children, appropriate for paediatric clinical use, were derived for growth from ages 7 to 18 years and a series of gender- and race-specific figures present the median velocity curves for children by year of maturation.
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