scispace - formally typeset
Search or ask a question

Showing papers in "The Journal of Pediatrics in 1985"


Journal ArticleDOI
TL;DR: Longitudinally-based height and height velocity charts for North American children are presented, suitable for following an individual child's progress during observation or treatment throughout the growth period, including puberty.

992 citations


Journal ArticleDOI
TL;DR: It is demonstrated that food hypersensitivity plays a pathogenic role in some children with atopic dermatitis and that appropriate diagnosis and exclusionary diets can lead to significant improvement in their skin symptoms.

674 citations


Journal ArticleDOI
TL;DR: The relationship between creatinine clearance and body habitus in 212 girls and 356 boys, including 181 boys and 69 girls between 13 and 21 years of age, was reexamined and the use of formula Ccr = k L/Pcr, where k = 0.55 resulted in a significant underestimation of GFR in adolescent boys but was suitable for girls.

363 citations


Journal ArticleDOI
Edward B. Blau1
TL;DR: Granulomatous disease of the skin, eyes, and joints is probably a new syndrome and the major long-term problems are iritis and joint contractures.

354 citations


Journal ArticleDOI
TL;DR: It is concluded that previously healthy infants younger than 3 months with an acute illness are unlikely to have serious bacterial infection if they have no findings consistent with ear, soft tissue, or skeletal infections and have normal white blood cell and band form counts and normal urine findings.

326 citations


Journal ArticleDOI
TL;DR: The efficacy of treatment with human surfactant in preterm infants with severe respiratory distress syndrome is confirmed and pneumothorax, pulmonary interstitial emphysema, and need for FiO2 greater than or equal to 0.3 for greater than 30 days was significantly less in the surfactan group.

293 citations


Journal ArticleDOI
TL;DR: Using morphometric techniques, lung structure, especially the arterial bed, in seven infants who died within 1 week of surgical repair was analyzed, finding that persistent hypoxemia in the no-honeymoon group is based on both severity of pulmonary hypoplasia and structural remodeling of the pulmonary arteries.

260 citations


Journal ArticleDOI
TL;DR: The results of this investigation suggest that P. cepacia colonization of patients with CF was endemic in the hospital, occurred more frequently in those with severe disease, and was associated with adverse clinical outcome.

245 citations


Journal ArticleDOI
TL;DR: Estimates were made to determine sunshine exposure conditions necessary to maintain serum 25-OHD concentrations above the lower limit of the normal range (11 ng/ml), and a conservative estimate would be 30 minutes per week wearing only a diaper or 2 hours a week fully clothed without a hat.

239 citations


Journal ArticleDOI
TL;DR: Children with spina bifida, sickle cell disease, or epilepsy, and children with the added burden of low socioeconomic status, were at particular risk for poor school achievement.

228 citations


Journal ArticleDOI
TL;DR: Of a cohort of 308 children with homozygous sickle cell disease diagnosed at birth, 89 experienced 132 clinically significant attacks of acute splenic sequestration (ASS) over a 10-year period, and the improvement in outcome is likely to have resulted from improvement in medical management and earlier detection of ASS.

Journal ArticleDOI
TL;DR: Dietary vitamin K~ is certainly the main, if not the only, source in human infants; contrary to what is commonly taught, colonic absorption of bacterially-produced menaquinones is unproven.

Journal ArticleDOI
TL;DR: The data suggest that a sudden fall in erythrocyte sedimentation rate or in platelet and fibrinogen levels may mark the start of this complication and may be an indication for rapid steroid therapy.

Journal ArticleDOI
TL;DR: The exposure of the infant is minimal, and breast-feeding may be permitted at maternal prednisolone doses of at least 20 mg once or twice daily, and at higher doses, exposure may be minimized if nursing is performed greater than 4 hours after the dose.

Journal ArticleDOI
TL;DR: School-aged children with newly diagnosed insulin-dependent diabetes mellitus (IDDM) were studied longitudinally in order to document how they adjusted to the medical illness and to assess salient background factors.

Journal ArticleDOI
TL;DR: It is confirmed that pediatric patients with AIDS have significant abnormalities in humoral immunity, and Dysfunction of both T cells and B cells plays a role in the resultant poor specific antibody production.

Journal ArticleDOI
TL;DR: It is suspected that the early sexual development in Puerto Rico is caused by exogenous estrogen contamination in the food ingested by the children and by their mothers.

Journal ArticleDOI
TL;DR: Significantly fewer children who had received either penicillin or cefadroxil had persistence of each of the three objective signs and each ofThe three subjective symptoms in GABHS pharyngitis than did children who received placebo.

Journal ArticleDOI
TL;DR: There was a tendency for plasma morphine concentrations to decrease in some patients receiving a constant infusion rate, suggesting improvement in morphine clearance rate and because of the apparently greater sensitivity to morphine and the lower elimination rate in newborn infants, the infused dose should not exceed 15 micrograms/kg/hr.

Journal ArticleDOI
TL;DR: The effects of adding exercise to diet for weight control in obese children were evaluated by randomizing obese girls to one of two groups: diet and diet plus exercise, with significant decreases from baseline weight and in percent overweight observed.

Journal ArticleDOI
TL;DR: The significant serum concentrations and urinary excretion rates of nicotine in the breast-fed infants of smoking mothers suggest that nursing contributes to the nicotine exposure of these neonates and the wide variation of cotinine excretion values did not allow separate evaluation of the two exposure routes.

Journal ArticleDOI
TL;DR: It is concluded that epidemic infantile winter diarrhea associated with human rotaviruses can be significantly reduced by vaccination with the live attenuated RIT 4237 bovine rotavirus vaccine before the epidemic season.

Journal ArticleDOI
TL;DR: There was a marked increase in patient ability to participate in activities of daily living, even in those patients in whom pulmonary function deteriorated during the study.

Journal ArticleDOI
TL;DR: It is concluded that these preterm infants have a distinct variety of hypokalemic tubular disorders rather than a variant of Bartter syndrome, because renal and systemic hyperprostaglandinism ranks high in the pathogenic chain of events, and the suppression of PGE2 hyperactivity is associated with significant improvement in the development and probably in the prognosis of the affected children.

Journal ArticleDOI
TL;DR: It is concluded that a relative deficiency of growth hormone in pubertal patients with Turner syndrome may contribute to their adult short stature.

Journal ArticleDOI
TL;DR: A multiple regression analysis of indicators of pubertal development with age, age at first transfusion, ageAt splenectomy, number of transfusions, serum transaminase and ferritin, and duration and intensity of chelation therapy failed to identify the factors responsible for the variation observed in sexual maturation among patients with thalassemia.

Journal ArticleDOI
TL;DR: It is postulate that CPAP reduces apnea in preterm infants by relief of upper airway obstruction, possibly via splinting of the pharyngeal airway.

Journal ArticleDOI
TL;DR: The 14-fold increase in prolonged apnea frequency immediately following regurgitation supports the hypothesis for a causal relationship between apnea and Regurgitation.

Journal ArticleDOI
TL;DR: Significant neonatal predictors of hearing loss in high-risk premature infants (less than or equal to 36 weeks gestation), as determined by multivariable testing, were prolonged respirator care, high serum bilirubin concentration, and hyponatremia.

Journal ArticleDOI
TL;DR: Cord length had a positive correlation with maternal height, pregravid weight, pregnancy weight gain, socioeconomic status, and the fetus being male, and short cords were associated with subsequent psychomotor abnormalities.