Journal ArticleDOI
Radiolabelling with organomercury compounds. Part 1. The synthesis and structure of 6-halocholest-5-en-3β-ols
Richard J. Flanagan,F. Peter Charleson,Eyvind I. Synnes,Leonard I. Wiebe,Yvon Theriault,Thomas T. Nakashima +5 more
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TLDR
The synthetic route to 6-chloromercuricholest-5-en-3β-ol has been studied and the yield improved from 2% to 20% as discussed by the authors.Abstract:
The synthetic route to 6-chloromercuricholest-5-en-3β-ol has been studied and the yield improved from 2% to 20%. The reaction of 6-chloromercuricholest-5-en-β-ol with fluorine, chlorine, bromine, a...read more
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Journal ArticleDOI
Radiohalogenation of proteins: An overview of radionuclides, labeling methods and reagents for conjugate labeling
TL;DR: It is clear that radiohalogenated conjugates of proteins can offer an advantage over direct labeling in that conjugating may be designed which provide some control over in vivo stability and secondary distribution of metabolites.
Journal ArticleDOI
The synthesis of radiolabeled compounds via organometallic intermediates
TL;DR: In this article, the authors discuss the utilisation of boranes, alanes, silanes, germanes, stannanes, and reactifs de Grignard.
Journal ArticleDOI
Synthesis and iodination of methyl 4-tri-n-butylstannylbenzoate, p-(methoxycarbonyl)phenylmercuric chloride and p-(methoxycarbonyl)phenylboronic acid
TL;DR: In this paper, the synthesis of methyl 4-tri-n-butylstannylbenzoate with hexabutylditin and palladium catalyst was performed by using aryl mercuric halides.
Journal ArticleDOI
The reactions of palladium(II), thallium(III) and lead(IV) trifluoroacetates with 3β-acetoxyandrost-5-en-17-one: crystal structure of the first trifluoroacetate bridged 5,6,7-π-allyl steroid palladium dimer
TL;DR: 3beta-Acetoxy-5alpha,6beta-bis(trifluoroacetoxy)androstan-17-one, a new compound, was also formed in this reaction, and during the course of the lead(IV) studies the dichlorosteroid 21 and the rearranged allylic oxidation product 24 were formed.
Journal ArticleDOI
Radiobromine and radioiodine for medical applications
D. Scott Wilbur,Michael J. Adam +1 more
TL;DR: In this article, the emission properties of radiobromine and radioiodine nuclides with half-lives longer than 1 h are summarized along with properties that make radionuclides useful in PET/SPECT imaging and β/Auger therapy, such that the reader can assess which of the radions might be useful for medical applications.
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