Journal ArticleDOI
Reactions of boroxazolidones with aromatic aldehydes: an easy route to derivatives of isoquinoline and iso-indolinone
TLDR
In this article, Boroxazolidones derived from glycine and phenylalanine react with aromatic aldehydes to form the corresponding imines, and these reactions proceed via carboxylic acids via catalytic, hydrogenation.About:
This article is published in Tetrahedron.The article was published on 1985-01-01. It has received 16 citations till now. The article focuses on the topics: Isoquinoline & Dicyclohexylamine.read more
Citations
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Journal ArticleDOI
Palladium-Catalysed Heteroannulation with Terminal Alkynes: a Highly Regio- and Stereoselective Synthesis of (Z)-3-Aryl(alkyl)idene Isoindolin-1-ones
Nitya G. Kundu,M. Wahab Khan +1 more
TL;DR: In this paper, a highly regio-and stereoselective method for the synthesis of (Z)-3-aryl(alkyl)idene isoindolin-1-ones through palladium-copper catalysis is described.
Journal ArticleDOI
Crystallization-Induced Asymmetric Transformation vs Quasi-Racemate Formation in Tetravalent Boron Complexes
TL;DR: In this paper, a mixture of diastereomers crystallizes under equilibrium conditions to afford a quasi-racemate 24, containing both diastereromers in the unit cell, and methylation occurs to give 26a.
Journal ArticleDOI
9-BBN: An amino acid protecting group for functionalization of amino acid side chains in organic solvents.
Dent William Hunter,W. Randal Erickson,Stephen Craig Fields,and Marshall H. Parker,Eric G. Tromiczak +4 more
TL;DR: 9-Borabicyclononane (9-BBN) has been utilized to protect functionalized amino acids for potential chemoselective side chain manipulation and is tolerant of a wide range of reaction conditions.
Patent
Antibiotics containing borinic acid complexes and methods of use
Ving J. Lee,Stephen J. Benkovic,Stephen J. Baker,Kirk R. Maples,Tsutomu Akama,Yong-Kang Zhang,Rajeshwar Singh,Vittorio A. Sauro,Chetan Pandit,Zhuoyi Su,Zhixiang Yang +10 more
TL;DR: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
Journal ArticleDOI
A novel approach for highly regio- and stereoselective synthesis of (Z)-3-methyleneisoindoline-1-ones in aqueous micellar medium
TL;DR: An environmentally benign and operationally simple methodology was developed for the regio-and stereoselective synthesis of (Z )-3-methyleneisoindolinones in aqueous micellar medium from 2-iodo- N -phenyl-benzamides and terminal alkyne by Cu-free domino Sonogashira reaction followed by 5-exo-dig-cyclization using Pd(CH 3 CN)Cl 2 as catalyst and 1,4-bis(4-pyridyl)-2,3-diaza
References
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Journal ArticleDOI
Boroxazolidones as simultaneous protection of the amino and carboxyl group in α-amino acids
TL;DR: In this paper, the synthesis of boroxazolidines form a variety of α-amino acids, which can serve as protected α-AMino acids in which the αamino and the carboxyl function are simultaneously blocked, while the side chain remains free for further reactions.
Journal ArticleDOI
Carbonboron bond cleavage by amino acids: An improved route to mixed anhydrides of diphenylborinic and amino acids
TL;DR: In this article, the carbon boron bonds of tetraphenylborate artion are sequentially cleaved by amino acids to yield diphenyl-borinic acid which, under the conditions of the reaction, is intercepted by the amine acid present to yield the corresponding mixed anhydride.
Journal ArticleDOI
Reactions of boroxazolidones with aromatic aldehydes
G.H.L. Nefkens,B. Zwanenburg +1 more