Open AccessJournal Article
Regulation of wound-healing angiogenesis-effect of oxygen gradients and inspired oxygen concentration
TLDR
These experiments demonstrate that: (1) A hypoxic tissue gradient is mandatory for wound-healing angiogenesis, (2) when the hypoxic gradient is destroyed capillary growth cases, and (3) inspired oxygen concentrations affect the rate and density of capillary Growth.About:
This article is published in Surgery.The article was published on 1981-08-01 and is currently open access. It has received 654 citations till now. The article focuses on the topics: Angiogenesis & Wound healing.read more
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Growth factors and cytokines in wound healing.
TL;DR: A review of the specific roles of these growth factors and cytokines during wound healing can be found in this article, where patients are treated by three growth factors: PDGF-BB, bFGF, and GM-CSF.
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Platelet-rich plasma: Growth factor enhancement for bone grafts
Robert E. Marx,Eric R. Carlson,Ralph M. Eichstaedt,Ralph M. Eichstaedt,Steven R Schimmele,Steven R Schimmele,James E. Strauss,Karen R. Georgeff +7 more
TL;DR: Monoclonal antibody assessment of cancellous cellular marrow grafts demonstrated cells that were capable of responding to the growth factors by bearing cell membrane receptors and evidenced a radiographic maturation rate 1.62 to 2.16 times that of grafts without platelet-rich plasma.
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Regulation of angiogenesis by hypoxia: role of the HIF system.
TL;DR: The role of HIF in developmental, adaptive and neoplastic angiogenesis, and the implications of oncogenic activation of extensive, physiologically interconnected hypoxia pathways for the tumor phenotype are discussed.
Journal ArticleDOI
Wound microbiology and associated approaches to wound management.
TL;DR: A detailed analysis of wound microbiology, together with current opinion and controversies regarding wound assessment and treatment, has attempted to capture and address microbiological aspects that are critical to the successful management of microorganisms in wounds.
Journal ArticleDOI
Continuous and Discrete Mathematical Models of Tumor-induced Angiogenesis
TL;DR: This paper presents both continuous and discrete mathematical models which describe the formation of the capillary sprout network in response to chemical stimuli supplied by a solid tumor and takes into account essential endothelial cell-extracellular matrix interactions via the inclusion of the matrix macromolecule fibronectin.
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