Relation of vigorous exercise to risk of atrial fibrillation.
Anthony Aizer,Anthony Aizer,J. Michael Gaziano,Nancy R. Cook,Nancy R. Cook,JoAnn E. Manson,JoAnn E. Manson,Julie E. Buring,Christine M. Albert +8 more
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In this article, the association between frequency of vigorous exercise and risk of developing atrial fibrillation in 16,921 apparently healthy men in the Physicians' Health Study was investigated.Abstract:
Limited data suggest that athletes may have a higher risk of developing atrial fibrillation (AF); however, there has been no large prospective assessment of the relation between vigorous exercise and AF. Logistic regression analyses stratified by time were used to assess the association between frequency of vigorous exercise and risk of developing AF in 16,921 apparently healthy men in the Physicians' Health Study. During 12 years of follow-up, 1,661 men reported developing AF. With increasing frequency of vigorous exercise (0, 1, 1 to 2, 3 to 4, 5 to 7 days/week), multivariate relative risks for the full cohort were 1.0 (referent), 0.90, 1.09, 1.04, and 1.20 (p = 0.04). This risk was not significantly increased when exercise habits were updated or in models excluding variables that may be in the biological pathway through which exercise influences AF risk. In subgroup analyses, this increased risk was observed only in men <50 years of age (1.0, 0.94, 1.20, 1.05, 1.74, p <0.01) and joggers (1.0, 0.91, 1.03, 1.30, 1.53, p <0.01), where risks remained increased in all analyses. In conclusion, frequency of vigorous exercise was associated with an increased risk of developing AF in young men and joggers. This risk decreased as the population aged and was offset by known beneficial effects of vigorous exercise on other AF risk factors.read more
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Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation : population-based estimates
TL;DR: In this paper, the authors found that men had a 1.5-fold higher risk of developing atrial fibrillation than women after adjusting for age and other risk factors.
Journal ArticleDOI
Pulmonary Vein Denervation Enhances Long-Term Benefit After Circumferential Ablation for Paroxysmal Atrial Fibrillation
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TL;DR: It is suggested that adjunctive CVD during CPVA significantly reduces recurrence of AF at 12 months, particularly in patients with reflexes and CVD, who were less likely to have recurrent AF than those without reflexes.
Journal ArticleDOI
Catheter ablation of cardiac autonomic nerves for prevention of vagal atrial fibrillation.
Patrick Schauerte,Benjamin J. Scherlag,Jan Pitha,Michael A. Scherlag,Dwight Reynolds,Ralph Lazzara,Warren M. Jackman +6 more
TL;DR: Transvascular atrial parasympathetic nerve system modification by RFCA abolishes vagally mediated AF and may provide a foundation for investigating the usefulness of neural ablation in chronic animal models of AF and eventually in patients with AF and high vagal tone.
Journal ArticleDOI
Prevalence and clinical significance of left atrial remodeling in competitive athletes.
Antonio Pelliccia,Barry J. Maron,Fernando M. Di Paolo,Alessandro Biffi,Filippo M. Quattrini,Cataldo Pisicchio,Alessandra Roselli,Stefano Caselli,Franco Culasso +8 more
TL;DR: In this article, the distribution and clinical significance of the left atrial (LA) size in the context of athlete's heart and the differential diagnosis from structural atrial structural hea...
Journal ArticleDOI
A mail survey of physical activity habits as related to measured physical fitness
Harold W. Kohl,Steven N. Blair,Ralph S. Paffenbarger,Caroline A. Macera,Jennie Jacobs Kronenfeld +4 more
TL;DR: In this article, the associations of self-reported measures of physical activity from a mail survey with an objective measure of physical fitness were investigated, which indicated that exercise behavior can be accurately estimated in large populations by using simple questions in a mail questionnaire.